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[[Image:Primary Follicle.jpg|thumb|right|150px|Histological Section of the Ovary showing Characteristics of the Primary Follicle- Courtesy of J.Bredl, Copyright RVC 2008]]
 
[[Image:Primary Follicle.jpg|thumb|right|150px|Histological Section of the Ovary showing Characteristics of the Primary Follicle- Courtesy of J.Bredl, Copyright RVC 2008]]
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*Oocyte surrounded by a single layer of follicular cuboidal cells.
 
*Oocyte surrounded by a single layer of follicular cuboidal cells.
 
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* The primary follicle will develop into a secondary follicle.
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** Granulosa cells proliferate into multiple layers and at the end of this the oocyte is fully grown.
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* Events that characterize this transition are:
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**Thecal layer becomes organised into the Theca Interna and the Theca Externa
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**Vascularisation of the theca
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* If gonadotrophins (LH and FSH) are removed, this transition still takes place.
     
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