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→Side Effects and Contraindications
==Side Effects and Contraindications==
==Side Effects and Contraindications==
This group of antibiotics on the whole are very safe.
* It has been known to cause acute anaphylaxis or mild hypersensitive reactions.
* High intravenous doses can lead to platelet dysfunction.
* Penicillins containing procaine musn't be given I.V. or with sulphonamides (they antagonise the action of sulphonamides.)
* Care must be taken when giving narrow spectrum penicillins to Guinea Pigs, Rabbits, Gerbils, Hamsters and Chinchillas as they can result in '''fatal ''Clostridium difficile'' colitis'''.