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Sulphonamides are derivatives of sulphanilamide, an active metabolite of the pro-drug and dye prontosil.

Sulphonamides are derivatives of sulphanilamide, an active metabolite of the pro-drug and dye prontosil. Commonly used ones are; '''sulphadiazine, sulphaquinoxaline, sulphadimethoxine, sulphadoxine''' and '''sulphanilamide'''.

* They are eliminate both by hepatic metabolism and renal excretion, the rate of both in each species and for each drug varies. This results in very different half-lives of each drug in each species.  

* They are eliminate both by hepatic metabolism and renal excretion, the rate of both in each species and for each drug varies. This results in very different half-lives of each drug in each species.  

* They are unable to work in pus or tissue debris as they contain thymidine and purines. This means that the bacteria can utilise these rather than folic acid for continued growth. This means that the drug will become obselete in such a circumstance.

* They are unable to work in pus or tissue debris as they contain thymidine and purines. This means that the bacteria can utilise these rather than folic acid for continued growth. This means that the drug will become obselete in such a circumstance.

==Side Effects and Contraindications==

==Side Effects and Contraindications==