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Trimethoprim - Dihydrofolate Reductase Inhibitors (view source)
Revision as of 12:50, 24 October 2008
, 12:50, 24 October 2008New page: {{unfinished}} {{toplink |linkpage =WikiDrugs |linktext =WikiDrugs |sublink1 = Antibiotics |subtext1 = Antibiotics |pagetype = Drugs }} [[Image: Trimethoprim.png|thumb|right|250px|Trimeth...
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{{toplink
|linkpage =WikiDrugs
|linktext =WikiDrugs
|sublink1 = Antibiotics
|subtext1 = Antibiotics
|pagetype = Drugs
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[[Image: Trimethoprim.png|thumb|right|250px|Trimethoprim]]
==Mechanism of Action==
Sulphonamides act by competing with an essential precursor in folic acid synthesis in bacteria. Bacteria need to synthesise folic acid in order to grow as they are unable to obtain it from their 'diet' like mammals can. Since the bacteria is unable to synthesise RNA or DNA, due to it's lack of folic acid, it's growth is inhibited. As such sulphonamides are '''bacteriostatic'''.
==Spectrum of Activity==
==Pharmacokinetic Considerations==
==Side Effects and Contraindications==
{{toplink
|linkpage =WikiDrugs
|linktext =WikiDrugs
|sublink1 = Antibiotics
|subtext1 = Antibiotics
|pagetype = Drugs
}}
[[Image: Trimethoprim.png|thumb|right|250px|Trimethoprim]]
==Mechanism of Action==
Sulphonamides act by competing with an essential precursor in folic acid synthesis in bacteria. Bacteria need to synthesise folic acid in order to grow as they are unable to obtain it from their 'diet' like mammals can. Since the bacteria is unable to synthesise RNA or DNA, due to it's lack of folic acid, it's growth is inhibited. As such sulphonamides are '''bacteriostatic'''.
==Spectrum of Activity==
==Pharmacokinetic Considerations==
==Side Effects and Contraindications==