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*Increase in pancreatic digestive enzymes (amylase, lipase, trypsin-like immunoreactivity (TLI), phospholipase A2 and pancreatic lipase immunoreactivity (PLI))
*Increase in pancreatic digestive enzymes (amylase, lipase, trypsin-like immunoreactivity (TLI), phospholipase A2 and pancreatic lipase immunoreactivity (PLI))
===Pancreas-specific laboratory tests===
===Pancreas-specific laboratory tests===
All pancreatic enzymes increase following renal failure (apart from PLI) making it difficult to determine the true cause of the increase. However increases of three fold are mainly due to pancreatitis, whereas five fold increases are rarely not found to be pancreatitis. Rises in lipase, amylase and phospholipase A2 may also be hepatic, gastric, intestinal or neoplastic in origin.
'''In cats:''' Amylase and lipase are of no diagnostic value,
'''In dogs:''' Lipase is a more reliable marker than amylase. However corticosteroid administartion raises lipase activity by up to five fold.
===Diagnostic Imaging===
===Diagnostic Imaging===
'''Survey Radiography''': Rarely helpful but findings may include:
'''Survey Radiography''': Rarely helpful but findings may include: