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===Acid-base correction===
===Acid-base correction===
Imbalances should be corrected after taking a blood gas reading.
Imbalances should be corrected after taking a blood gas reading.
*If metabolic acidotic: give sodium bicarbonate (1mmol/kg), but do repeated blood gas
*If metabolic acidotic: give sodium bicarbonate but do repeated blood gas
*If metabolic alkalosis: replace volume defecit with intravenous NaCl and KCl.
*If metabolic alkalosis: replace volume defecit with intravenous NaCl and KCl.
*Blocking of acid secretion:
*Blocking of acid secretion:
**[[Gastroprotective Drugs#Histamine (H2) Receptor Antagonists|Histamine receptor antagonists]]:
**[[Gastroprotective Drugs#Histamine (H2) Receptor Antagonists|Histamine receptor antagonists]]:
***cimetidine (10 mg/kg, per os (PO)/intramuscular (IM)/intravenous (IV), three times daily (tid)
***cimetidine
***ranitidine (Dogs: 2 mg/kg, PO/IV, tid. Cats: 2.5 mg/kg, IV two times daily (bid) or 3.5 mg/kg, PO bid
***ranitidine
***famotidine (0.5-1 mg/kg, PO/IV, once daily (sid)-bid
***famotidine
**Gastrin antagonists:
**Gastrin antagonists:
***proglumide
***proglumide
***pirenzepine
***pirenzepine
**Adenyl cyclase inhibitors:
**Adenyl cyclase inhibitors:
***[[Gastroprotective Drugs#Prostaglandin E Analogues|prostaglangin E2 (PGE) analogues]] (misoprostol (Dogs: 2-5µg/kg PO tid)
***[[Gastroprotective Drugs#Prostaglandin E Analogues|prostaglangin E2 (PGE) analogues]] (misoprostol)
**[[Gastroprotective Drugs#Proton Pump Inhibitors|H<sup>+</sup>:K<sup>+</sup>ATPase inhibitors ]]:- for use when patient is refractory to histamine antagonists
**[[Gastroprotective Drugs#Proton Pump Inhibitors|H<sup>+</sup>:K<sup>+</sup>ATPase inhibitors ]]:- for use when patient is refractory to histamine antagonists
***omeprazole (0.7 mg/kg PO sid) - good for exercise induced gastric ulceration
***omeprazole - good for exercise induced gastric ulceration
===Mucosal protectants===
===Mucosal protectants===
Such as misoprostol can be given alongside [[NSAIDs|NSAIDs]] to decrease the risk of ulceration. '''[[Gastroprotective Drugs#Binding Agents|Sucralfate]]''' (Dogs: 0.5-1g PO bid/tid. Cats: 0.25g PO bid/tid) which is polyaluminium sucrose sulphate, binds to damaged mucosa and assists in the treatment of gastric ulceration. It is best given 2 hours after acid inhibitors to prevent interference.
Such as misoprostol can be given alongside [[NSAIDs|NSAIDs]] to decrease the risk of ulceration. '''[[Gastroprotective Drugs#Binding Agents|Sucralfate]]''' which is polyaluminium sucrose sulphate, binds to damaged mucosa and assists in the treatment of gastric ulceration. It is best given 2 hours after acid inhibitors to prevent interference.
===Prophylaxis===
===Prophylaxis===