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==Signalment==

==Signalment==

**[[Canine Breeds - WikiNormals #Working Group|Rottweiler]]

**[[Canine Breeds - WikiNormals #Working Group|Rottweiler]]

**[[Canine Breeds - WikiNormals #Terrier Group|Soft Coated Wheaten Terriers]]

**[[Canine Breeds - WikiNormals #Terrier Group|Soft Coated Wheaten Terriers]]

==Description==

==Description==

Lymphangiectasia often accompanies a lipogranulomatous [[Inflammation - Pathology|inflammation]], but it is not clear which is the primary event.  [[Oedema - Pathology#Lymphatic oedema|Lymphangitis]] can cause lymphatic obstruction but the leakage of [[Lymph - Anatomy & Physiology|lymph]] can also cause a [[Chronic Inflammation  - Pathology#Granulomatous Inflammation|granuloma]] to form.

Lymphangiectasia often accompanies a lipogranulomatous [[Inflammation - Pathology|inflammation]], but it is not clear which is the primary event.  [[Oedema - Pathology#Lymphatic oedema|Lymphangitis]] can cause lymphatic obstruction but the leakage of [[Lymph - Anatomy & Physiology|lymph]] can also cause a [[Chronic Inflammation  - Pathology#Granulomatous Inflammation|granuloma]] to form.

==Diagnosis==

==Diagnosis==

It is essential to distinguish a true lymphangiectasia from a secondary lacteal dilation due to [[Inflammatory Bowel Disease - WikiClinical|Inflammatory Bowel Disease ]] (IBD).  In the case of IBD, inflammatory infiltrate will be seen in the lamina propria, but the degree of infiltration may be underestimated if [[Oedema - Pathology|oedema]] is present.

It is essential to distinguish a true lymphangiectasia from a secondary lacteal dilation due to [[Inflammatory Bowel Disease - WikiClinical|Inflammatory Bowel Disease ]] (IBD).  In the case of IBD, inflammatory infiltrate will be seen in the lamina propria, but the degree of infiltration may be underestimated if [[Oedema - Pathology|oedema]] is present.

==Treatment==

==Treatment==

*Identify and treat the underlying cause if it is a secondary lymphangiectasia

*Identify and treat the underlying cause if it is a secondary lymphangiectasia

*Fat-restricted diet

*Fat-restricted diet

**The diet needs to be calorific and highly digestible

*The diet needs to be calorific and highly digestible

*Supplementation of fat soluble vitamins

*Supplementation of fat soluble vitamins

*Anecdotal report of glutamine supplementation

*Anecdotal report of glutamine supplementation

*[[Steroids|Prednisolone]] at 1-2 mg/kg/day PO

 

**[[Anti-Inflammatory Drugs|Anti-inflammatory]] and immunosuppressive effect may be beneficial

**This is particularly true if there is associated lymphangitis, lipogranulomas or a [[Lymphocytic - Plasmacytic Enteritis - WikiClinical|lymphocytic-plasmacytic]] infiltration of the lamina propria.

*[[Steroids|Prednisolone]]

**Azathioprine at 2.2 mg/kg q48 hours or Ciclosporin at 3-5 mg/kg q24 to 12 hours can also be considered

*[[Anti-Inflammatory Drugs|Anti-inflammatory]] and immunosuppressive effect may be beneficial.

*Antimicrobials such as metronidazole or tylosin  

*This is particularly true if there is associated lymphangitis, lipogranulomas or a [[Lymphocytic - Plasmacytic Enteritis - WikiClinical|lymphocytic-plasmacytic]] infiltration of the lamina propria.

**This may be beneficial due to their potential immunomodulatory effect and modulation of the enteric flora

*Azathioprine at 2.2 mg/kg q48 hours or Ciclosporin at 3-5 mg/kg q24 to 12 hours can also be considered

 

*[[Nitroimidazoles|Metronidazole]] or [[Macrolides and Lincosamides|tylosin]] can be given

*This may be beneficial due to their potential immunomodulatory effect and modulation of the enteric flora

*Diuretics such as [[Treatment of Heart Failure - WikiClinical #C. Pharmacological|frusemide]] and [[Treatment of Heart Failure - WikiClinical #C. Pharmacological|spironolactone]] are used to manage effusions.

*Diuretics such as [[Treatment of Heart Failure - WikiClinical #C. Pharmacological|frusemide]] and [[Treatment of Heart Failure - WikiClinical #C. Pharmacological|spironolactone]] are used to manage effusions.

*Short term treatment with [[Plasma - WikiBlood|plasma]] or [[Colloids|colloids]] can be given for plasma expansion.

*Short term treatment with [[Plasma - WikiBlood|plasma]] or [[Colloids|colloids]] can be given for plasma expansion.

==Prognosis==

==Prognosis==