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Sulphonamides (view source)

Revision as of 02:27, 8 September 2009

2 bytes removed , 02:27, 8 September 2009

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==Mechanism of Action==

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Sulphonamides act by competing with an essential precursor in folic acid synthesis in bacteria. Bacteria need to synthesise folic acid in order to grow as they are unable to obtain it from their 'diet' like mammals can. Since the ~~bacteria~~ is unable to ~~synthesise~~ RNA or DNA, due to ~~it's~~ lack of folic acid, ~~it's~~ growth is inhibited. As such sulphonamides are '''bacteriostatic'''.

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Sulphonamides act by competing with an essential precursor in folic acid synthesis in bacteria. Bacteria need to synthesise folic acid in order to grow as they are unable to obtain it from their 'diet' like mammals can. Since the bacterium is unable to synthesize RNA or DNA, due to its lack of folic acid, its growth is inhibited. As such, sulphonamides are '''bacteriostatic'''.

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==Spectrum of Activity==

Amazonian

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