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|sublink1=Alimentary Flashcards - Pathology
 
|sublink1=Alimentary Flashcards - Pathology
 
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}}
<br>
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<FlashCard questions="21">
==Introduction==
+
|q1=Liver lesions are common because:
 
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|a1=it is an area of high metabolic activity<br>Receives toxic agents from the gut via the portal blood system<br>Has an extensive vascular supply (prime site for metastatic disease)
*This Page contains Flashcards for the pathology of the [[Liver - Pathology|Liver]]
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|l1=Liver General Pathology - Pathology#Introduction
 
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|q2=In each type of jaundice, will bilirubinuria be detected?
*In order to reveal an answer, highlight the underlined or bulleted area using your mouse.
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* Haemolytic
 
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* Obstructive
*The number of bullet points doesn't necessarily indicate a strict number of answers.
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* Hepatocellular
 
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|a2=NO - because most of bilirubin is unconjugated<br>YES - because conjugated bilirubin accumulates<br>NO - because bilirubin fails to conjugate due to liver cell damage<br>NB - the kidney can only excrete the water soluble conjugate
*Internet explorer is different - you'll have to guess where the underline should be!
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|l2=Liver General Pathology - Pathology#Jaundice (Icterus)
 
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|q3=In regards to secondary photosensitisation, what are two hepatotoxic plants?
==Flashcards==
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|a3=Senecio jacobea (Ragwort)<br>Lantana camara (Lantana)<br>Lupinus angustifolius (Lupins)<br>Blue-green algae
 
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|l3=Liver General Pathology - Pathology#secondary photosensitisation
{| border="3" cellpadding="8"
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|q4=What are two causes of necrosis?
!width="400"|'''Question'''
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|a4=severe metabolic disturbances<br>Nutritional deficiencies<br>Toxic substances<br>Actions of micro-organisms
!width="400"|'''Answer'''
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|l4=Liver General Pathology - Pathology#Necrosis
!width="150"|'''Article'''
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|q5=What can cause the liver to appear greenish-blue post mortem?
 
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|a5=bacteria degrades blood pigment to hydrogen sulfide
|-
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|l5=Liver Post Mortem - Pathology#Gross
|<big>'''Liver lesions are common because:
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|q6=True or false?
||<font color="white"> <big>
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Cranial displacements of the liver are the most common.
*'''''it is an area of high metabolic activity'''''
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|a6=false
*'''''receives toxic agents from the gut via the portal blood system'''''
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|l6=Liver Developmental - Pathology#Displacement
*'''''has an extensive vascular supply (prime site for metastatic disease)'''''
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|q7=What occurs during Congestion?
||[[Liver General Pathology - Pathology#Introduction|<span title="Answer article">Link to Answer Article</span>]]
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|a7=The right side of the heart fails to function properly and blood will back up through the veins into the liver.
|-
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|l7=Liver Circulatory Disturbances - Pathology#Passive congestion
 
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|q8=True or false?
|-
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Congenital melanosis in calves and lambs appears as white discoloration of small irregular portions of the liver.
|<big>'''In each type of jaundice, will bilirubinuria be detected?
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|a8=false
* '''haemolytic
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|l8=Liver Pigmentation - Pathology#Congenital melanosis
* '''obstructive
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|q9=Hepatic lipidosis or fatty liver syndrome is associated with?
* '''hepatocellular
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|a9=Dietary factors: obesity and starvation<br>Increased demand for energy: pregnancy, lactation, and starvation in physiological states<br>Diabetes mellitus, ketosis, and pregnancy toxaemia in pathological conditions<br>Abnormal hepatocytic function: prevents fatty acids from forming complexes with proteins to form low density lipoproteins for secretion into the blood
||<font color="white"> <big>
+
|l9=Liver Degenerative - Pathology#Hepatic lipidosis - fatty liver syndrome
*'''''NO - because most of bilirubin is unconjugated'''''
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|q10=What could be a non-pathological reason for a cow displaying fatty liver syndrome during necropsy?
*'''''YES - because conjugated bilirubin accumulates'''''
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|a10=It is possible to show fat infiltration of liver in cows which have not been eating for several days.
*'''''NO - because bilirubin fails to conjugate due to liver cell damage'''''
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|l10=Liver Degenerative - Pathology#Gross
*'''''NB - the kidney can only excrete the water soluble conjugate'''''
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|q11=True or false?
||[[Liver General Pathology - Pathology#Jaundice (Icterus)|<span title="Answer article">Link to Answer Article</span>]]
+
Equine hyperlipidemia or fat pony syndrome is similar to that in cats, as well as fatal within a week.
|-
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|a11=True
 
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|l11=Liver Degenerative - Pathology#Equine hyperlipidemia
 
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|q12=What causes Lysosomal storage disease and how does it manifest itself?
|-
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|a12=Due to an inherited deficiency of lysosomal enzymes<br>Manifest themselves as neurological disease
|<big>'''In regards to secondary photosensitisation, what are two hepatotoxic plants?
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|l12=Liver Storage Diseases - Pathology#Lysosomal storage diseases
||<font color="white"> <big>
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|q13=Herpes virus infections include -  
*'''''Senecio jacobea (Ragwort)'''''
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|a13=Equine Viral Rhinopneumonitis<br>Infectious Bovine Rhinotracheitis<br>Feline Viral Rhinopneumonitis<br>Aujesky's disease in pigs
*'''''Lantana camara (Lantana)'''''
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|l13=Liver Inflammatory - Pathology#Herpes virus infections
*'''''Lupinus angustifolius (Lupins)'''''
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|q14=You are examining a cow's liver post-necropsy.  You notice the liver has several small areas of necrosis.  Is this more likely to be Black Disease or Red Water Disease?  
*'''''Blue-green algae'''''
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|a14=Black Disease
||[[Liver General Pathology - Pathology#secondary photosensitisation|<span title="Answer article">Link to Answer Article</span>]]
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|l14=Liver Inflammatory - Pathology#Infectious Necrotic Hepatitis (Black Disease)
|-
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|q15=What are the two main types of Hepatitis in cats?
 
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|a15=Cholangiohepatitis<br>Lymphocytic portal hepatitis
|-
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|l15=Liver Inflammatory - Pathology#Hepatitis in cats
|<big>'''What are two causes of necrosis?
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|q16=True or false?
||<font color="white"> <big>
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Use of carbon tetrachloride as an anthelmintic and phosphorous as a rodenticide has never been proven to produce liver necrosis.
*'''''severe metabolic disturbances'''''
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|a16=False
*'''''nutritional deficiencies'''''
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|l16=Liver Toxic - Pathology#Acute hepatoxicity
*'''''toxic substances'''''
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|q17=Pyrrolizidine alkaloids have an anti-mitotic effect whilst allowing continued synthesis within the cell and its nucleus. This causes a marked increase in the size of parenchymal cells, a phenomenon termed -  
*'''''actions of micro-organisms'''''
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|a17=megalocytosis
||[[Liver General Pathology - Patholgoy#Necrosis|<span title="Answer article">Link to Answer Article</span>]]
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|l17=Liver Toxic - Pathology#Ragwort
|-
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|q18=What are the two most common primary hepatic neoplasms?
 
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|a18=Liver cell tumours<br>Malignant bile duct tumours
|-
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|l18=Liver Proliferative - Pathology#Primary tumours
|<big>'''What can cause the liver to appear greenish-blue post mortem?
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|q19=Haemangiosarcoma can be primary in the liver, what are other predilection sites?
||<font color="white"> <big>
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|a19=Spleen<br>Right auricle of the heart
*'''''bacteria degrades blood pigment to hydrogen sulfide'''''
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|l19=Liver Proliferative - Pathology#Haemangiosarcoma
||[[Liver Post Mortem - Pathology#Gross|<span title="Answer article">Link to Answer Article</span>]]
+
|q20=True or false?
|-
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Chronic lymphocytic cholangitis generally afflicts only very young cats.
 
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|a20=false
|-
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|l20=Liver Unknown Aetiology - Pathology#Chronic lymphocytic cholangitis
|<big>'''True or false?
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|q21=What are two causes of Cholangitis of the liver?
'''Cranial displacements of the liver are the most common.
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|a21=Ascending infections from the intestine<br>Associated with organisms excreted via the bile
||<font color="white"> <big>
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|l21=Liver Biliary Tract - Pathology#Cholangitis
*'''''false'''''
+
</FlashCard>
||[[Liver Developmental - Pathology#Displacement|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
 
  −
|-
  −
|<big>'''What occurs during Congestion?
  −
||<font color="white"> <big>
  −
*'''''The right side of the heart fails to function properly and blood will back up through the veins into the liver.
  −
||[[Liver Circulatory Disturbances - Pathology#Passive congestion|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
 
  −
|-
  −
|<big>'''True or false?
  −
'''Congenital melanosis in calves and lambs appears as white discoloration of small irregular portions of the liver.
  −
||<font color="white"> <big>
  −
*'''''false'''''
  −
||[[Liver Pigmentation - Patholgoy#Congenital melanosis|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
 
  −
|-
  −
|<big>'''Hepatic lipidosis or fatty liver syndrome is associated with -
  −
||<font color="white"> <big>
  −
*'''''dietary factors: obesity and starvation '''''
  −
*'''''increased demand for energy: pregnancy, lactation, and starvation in physiological states '''''
  −
*'''''Diabetes mellitus, ketosis, and pregnancy toxaemia in pathological conditions '''''
  −
*'''''abnormal hepatocytic function: prevents fatty acids from forming complexes with proteins to form low density lipoproteins for secretion into the blood '''''
  −
||[[Liver Degenerative - Pathology#Hepatic lipidosis - fatty liver syndrome|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
 
  −
|-
  −
|<big>'''What could be a non-pathological reason for a cow displaying fatty liver syndrome during necropsy?
  −
||<font color="white"> <big>
  −
*'''''It is possible to show fat infiltration of liver in cows which have not been eating for several days.
  −
||[[Liver Degenerative - Pathology#Gross|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
 
  −
|-
  −
|<big>'''True or false?
  −
'''Equine hyperlipidemia or fat pony syndrome is similar to that in cats, as well as fatal within a week.
  −
||<font color="white"> <big>
  −
*'''''true'''''
  −
||[[Liver Degenerative - Pathology#Equine hyperlipidemia|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
 
  −
|-
  −
|<big>'''What causes Lysosomal storage disease and how does it manifest itself?
  −
||<font color="white"> <big>
  −
*'''''due to an inherited deficiency of lysosomal enzymes'''''
  −
*'''''manifest themselves as neurological disease '''''
  −
||[[Liver Storage Diseases - Pathology#Lysosomal storage diseases|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
 
  −
|-
  −
|<big>'''Herpes virus infections include -
  −
||<font color="white"> <big>
  −
*'''''Equine Viral Rhinopneumonitis'''''
  −
*'''''Infectious Bovine Rhinotracheitis'''''
  −
*'''''Feline Viral Rhinopneumonitis'''''
  −
*'''''Aujesky's disease in pigs '''''
  −
||[[Liver Inflammatory - Pathology#Herpes virus infections|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
 
  −
|-
  −
|<big>'''You are examining a cow's liver post-necropsy.  You notice the liver has several small areas of necrosis.  Is this more likely to be Black Disease or Red Water Disease?
  −
||<font color="white"> <big>
  −
*'''''Black Disease'''''
  −
||[[Liver Inflammatory - Pathology#Infectious Necrotic Hepatitis (Black Disease)|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
 
  −
|-
  −
|<big>'''What are the two main types of Hepatitis in cats?
  −
||<font color="white"> <big>
  −
*'''''cholangiohepatitis'''''
  −
*'''''Lymphocytic portal hepatitis'''''
  −
||[[Liver Inflammatory - Pathology#Hepatitis in cats|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
 
  −
 
  −
|-
  −
|<big>'''True or false?
  −
'''Use of carbon tetrachloride as an anthelmintic and phosphorous as a rodenticide has never been proven to produce liver necrosis. 
  −
||<font color="white"> <big>
  −
*'''''false'''''
  −
||[[Liver Toxic - Pathology#Acute hepatoxicity|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
 
  −
|-
  −
|<big>'''Pyrrolizidine alkaloids have an anti-mitotic effect whilst allowing continued synthesis within the cell and its nucleus. This causes a marked increase in the size of parenchymal cells, a phenomenon termed -
  −
||<font color="white"> <big>
  −
*'''''megalocytosis'''''
  −
||[[Liver Toxic - Pathology#Ragwort|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
 
  −
|-
  −
|<big>'''What are the two most common primary hepatic neoplasms?
  −
||<font color="white"> <big>
  −
*'''''liver cell tumours'''''
  −
*'''''malignant bile duct tumours '''''
  −
||[[Liver Proliferative - Pathology#Primary tumours|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
 
  −
|-
  −
|<big>'''Haemangiosarcoma can be primary in the liver, what are other predilection sites?
  −
||<font color="white"> <big>
  −
*'''''spleen'''''
  −
*'''''right auricle of the heart'''''
  −
||[[Liver Proliferative - Pathology#Haemangiosarcoma|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
 
  −
|-
  −
|<big>'''True or false?
  −
'''Chronic lymphocytic cholangitis generally afflicts only very young cats.
  −
||<font color="white"> <big>
  −
*'''''false'''''
  −
||[[Liver Unknown Aetiology - Pathology#Chronic lymphocytic cholangitis|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
 
  −
|-
  −
|<big>'''What are two causes of Cholangitis of the liver?
  −
||<font color="white"> <big>
  −
*'''''ascending infections from the intestine'''''
  −
*'''''associated with organisms excreted via the bile'''''
  −
||[[Liver Biliary Tract - Pathology#Cholangitis|<span title="Answer article">Link to Answer Article</span>]]
  −
|-