no edit summary
Line 1: Line 1:  
{{toplink
 
{{toplink
|backcolour = f5fffa
   
|linkpage =Host invasion by microorganisms - WikiBlood
 
|linkpage =Host invasion by microorganisms - WikiBlood
 
|linktext =HOST INVASION BY MICROORGANISMS
 
|linktext =HOST INVASION BY MICROORGANISMS
Line 7: Line 6:  
|pagetype =Blood
 
|pagetype =Blood
 
}}
 
}}
<br>
+
===Host invasion===
==<font color="purple">Host invasion</font>==
+
<FlashCard questions="1">
{| border="3" cellpadding="8"
+
|q1=By what three routes can pathogens enter the body?
!width="400"|'''Question'''
+
|a1=
!width="400"|'''Answer'''
+
*Contact
!width="150"|'''Article'''
+
*Aerosol
|-
+
*Orofecal
|<big>'''By what three routes can pathogens enter the body?'''
+
|l1=Host invasion by microorganisms - WikiBlood
||<font color="white"> <big>
+
</FlashCard>
*'''''Contact'''''
+
===Viruses===
*'''''Aerosol'''''
+
<FlashCard questions="8">
*'''''Orofecal'''''
+
|q1=Naked viruses contain only...?
||[[Host invasion by microorganisms - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
+
|a1=RNA/DNA and protein coat
|}
+
|l1=Viruses - WikiBlood
 
+
|q2=Name three functions of viral structural proteins
 
+
|a2=
==<font color="purple">Viruses</font>==
+
*Protection of the genome
{| border="3" cellpadding="8"
+
*Attachment to host cell
!width="400"|'''Question'''
+
*Fusion of envelope to host cell membrane
!width="400"|'''Answer'''
+
|l2=Viruses - WikiBlood
!width="150"|'''Article'''
+
|q3=Name the two main innate defences against viral infection
|-
+
|a3=
|<big>'''Naked viruses contain only...?'''
+
*Interferon
||<font color="white"> <big>
+
*Natural killer cells
*'''''RNA/DNA and protein coat'''''
+
|l3=Viruses - WikiBlood
||[[Viruses - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
+
|q4=Upon viral infection, which antibody isotype is increased at mucosal surfaces?
|-
+
|a4=IgA
|<big>'''Name three functions of viral structural proteins'''
+
|l4=Viruses - WikiBlood
||<font color="white"> <big>
+
|q5=What do antibodies stop free virus particles from doing?
*'''''Protection of the genome'''''
+
|a5=Binding to host cell, entering and uncoating
*'''''Attachment to host cell'''''
+
|l5=Viruses - WikiBlood
*'''''Fusion of envelope to host cell membrane'''''
+
|q6=By what mechanism is complement able to damage the virion envelope?
||[[Viruses - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
+
|a6=Virolysis
|-
+
|l6=Viruses - WikiBlood
|<big>'''Name the two main innate defences against viral infection'''
+
|q7=When coupled with antibodies, what mechanisms does complement aid in immune defence?
||<font color="white"> <big>
+
|a7=
*'''''Interferon'''''
+
*Blocking the virus receptor
*'''''Natural killer cells
+
*Lysis of infected cells
||[[Viruses - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
+
*Opsonisation of free particles or infected cells
|-
+
|l7=Viruses - WikiBlood
|<big>'''Upon viral infection, which antibody isotype is increased at mucosal surfaces?'''
+
|q8=What are the main cytokines CD4+ T cells release to recruit macrophages?
||<font color="white"> <big>
+
|a8=
*'''''IgA'''''
+
*IFN-γ
||[[Viruses - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
+
*TNF
|-
+
|l8=Viruses - WikiBlood
|<big>'''What do antibodies stop free virus particles from doing?'''
+
</FlashCard>
||<font color="white"> <big>
+
===Bacteria===
*'''''Binding to host cell, entering and uncoating'''''
+
<FlashCard questions="8">
||[[Viruses - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
+
|q1=Describe three ways prokaryotic DNA differs from eukaryotic DNA
|-
+
|a1=
|<big>'''By what mechanism is complement able to damage the virion envelope?'''
+
*Few repeated sequences
||<font color="white"> <big>
+
*Most of the DNA is transcibed
*'''''Virolysis'''''
+
*No intervening sequences within structural genes
||[[Viruses - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
+
|l1=Bacteria - WikiBlood
|-
+
|q2=These surface components allow bacteria to move around
|<big>'''When coupled with antibodies, what mechanisms does complement aid in immune defence?'''
+
|a2=Flagella
||<font color="white"> <big>
+
|l2=Bacteria - WikiBlood
*'''''Blocking the virus receptor'''''
+
|q2=Bacteria with an outer layer of lipopolysaccharide are classed as...
*'''''Lysis of infected cells'''''
+
|a2=Gram-negative
*'''''Opsonisation of free particles or infected cells'''''
+
|l2=Bacteria - WikiBlood
||[[Viruses - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
+
|q3=Bacteria with a round shape are classed as...
|-
+
|a3=Cocci
|<big>'''What are the main cytokines CD4+ T cells release to recruit macrophages?'''
+
|l3=Bacteria - WikiBlood
||<font color="white"> <big>
+
|q4=Bacteria with a long shape are classed as...
*'''''IFN-γ'''''
+
|a4=Rods or bacilli
*'''''TNF'''''
+
|l4=Bacteria - WikiBlood
||[[Viruses - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
+
|q5=What are the four rules summarising the cause and effect relationship between bacteria and infection?
|}
+
|a5=Koch's postulates
 
+
|l5=Bacteria - WikiBlood
==<font color="purple">Bacteria</font>==
+
|q6=What is the condition, characterised by excessive cytokine production, that is caused by bacterial components such as LPS?
{| border="3" cellpadding="8"
+
|a6=Endotoxin shock
!width="400"|'''Question'''
+
|l6=Bacteria - WikiBlood
!width="400"|'''Answer'''
+
|q7=By what mechanism do most bacteria replicate?
!width="150"|'''Article'''
+
|a7=Binary fission
|-
+
|l7=Bacteria - WikiBlood
|<big>'''Describe three ways prokaryotic DNA differs from eukaryotic DNA'''
+
|q8=By what three mechanisms can bacteria transfer DNA?
||<font color="white"> <big>
+
|a8=
*'''''Few repeated sequences'''''
+
*Transformation
*'''''Most of the DNA is transcibed'''''
+
*Transduction
*'''''No intervening sequences within structural genes'''''
+
*Conjugation
||[[Bacteria - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
+
|l8=Bacteria - WikiBlood
|-
+
</FlashCard>
|<big>'''These surface components allow bacteria to move around'''
+
===Parasites===
||<font color="white"> <big>
+
<FlashCard questions="6">
*'''''Flagella'''''
+
|q1=Do protozoa have a eukaryotic or prokaryotic cell structure
||[[Bacteria - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
+
|a1=Eukaryotic
|-
+
|l1=Parasites - WikiBlood
|<big>'''Bacteria with an outer layer of lipopolysaccharide are classed as...'''
+
|q2=What are the two main groups of helminth parasite?
||<font color="white"> <big>
+
|a2=
*'''''Gram-negative'''''
+
*Nematodes
||[[Bacteria - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
+
*Platyhelminthes
|-
+
|l2=Parasites - WikiBlood
|<big>'''Bacteria with a round shape are classed as...'''
+
|q3=What is the main cell type that mediates the destruction of larger parasites?
||<font color="white"> <big>
+
|a3=Eosinophils
*'''''Cocci'''''
+
|l3=Parasites - WikiBlood
||[[Bacteria - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
+
|q4=What T cell subtype is required to fight intracellular protozoa
|-
+
|a4=Th1
|<big>'''Bacteria with a long shape are classed as...'''
+
|l4=Parasites - WikiBlood
||<font color="white"> <big>
+
|q5=What T cell subtype is required to fight intestinal worms?
*'''''Rods or bacilli'''''
+
|a5=Th2
||[[Bacteria - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
+
|l5=Parasites - WikiBlood
|-
+
|q6=How do antibodies defend against parasitic infection?
|<big>'''What are the four rules summarising the cause and effect relationship between bacteria and infection?'''
+
|a6=
||<font color="white"> <big>
+
*Directly damaging protozoa
*'''''Koch's postulates'''''
+
*Activating complement
||[[Bacteria - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
+
*Blocking attachment to host cells
|-
+
*Enhancing macrophage phagocytosis
|<big>'''What is the condition, characterised by excessive cytokine production, that is caused by bacterial components such as LPS?'''
+
*Antibody-dependent cell-mediated cytotoxicity
||<font color="white"> <big>
+
|l6=Parasites - WikiBlood
*'''''Endotoxin shock'''''
+
</FlashCard>
||[[Bacteria - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
|<big>'''By what mechanism do most bacteria replicate?'''
  −
||<font color="white"> <big>
  −
*'''''Binary fission'''''
  −
||[[Bacteria - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
|<big>'''By what three mechanisms can bacteria transfer DNA?'''
  −
||<font color="white"> <big>
  −
*'''''Transformation'''''
  −
*'''''Transduction'''''
  −
*'''''Conjugation'''''
  −
||[[Bacteria - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
  −
|}
  −
 
  −
==<font color="purple">Parasites</font>==
  −
{| border="3" cellpadding="8"
  −
!width="400"|'''Question'''
  −
!width="400"|'''Answer'''
  −
!width="150"|'''Article'''
  −
|-
  −
|<big>'''Do protozoa have a eukaryotic or prokaryotic cell structure'''
  −
||<font color="white"> <big>
  −
*'''''Eukaryotic'''''
  −
||[[Parasites - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
|<big>'''What are the two main groups of helminth parasite?'''
  −
||<font color="white"> <big>
  −
*'''''Nematodes'''''
  −
*'''''Platyhelminthes'''''
  −
||[[Parasites - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
|<big>'''What is the main cell type that mediates the destruction of larger parasites?'''
  −
||<font color="white"> <big>
  −
*'''''Eosinophils'''''
  −
||[[Parasites - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
|<big>'''What T cell subtype is required to fight intracellular protozoa'''
  −
||<font color="white"> <big>
  −
*'''''Th1'''''
  −
||[[Parasites - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
|<big>'''What T cell subtype is required to fight intestinal worms?'''
  −
||<font color="white"> <big>
  −
*'''''Th2'''''
  −
||[[Parasites - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
|<big>'''How do antibodies defend against parasitic infection?'''
  −
||<font color="white"> <big>
  −
*'''''Directly damaging protozoa'''''
  −
*'''''Activating complement'''''
  −
*'''''Blocking attachment to host cells'''''
  −
*'''''Enhancing macrophage phagocytosis'''''
  −
*'''''Antibody-dependent cell-mediated cytotoxicity'''''
  −
||[[Parasites - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
  −
|}
  −
<br>
  −
<br>
  −
<big><center>[[Host invasion by microorganisms - WikiBlood|'''BACK TO HOST INVASION BY MICROORGANISMS''']]</center></big>
  −
<big><center>[[Flash Cards - WikiBlood|'''BACK TO WIKIBLOOD FLASHCARDS''']]</center></big>