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Gastrointestinal Pharmacology quiz (view source)
Revision as of 18:03, 29 March 2010
, 18:03, 29 March 2010Created page with '{{toplink |linkpage =WikiQuiz |linktext = WikiQuiz |pagetype=Quiz |Review= '''Richard Hammond''' BSc BVetMed DipECVA DVA PhD MRCVS }}<br> <WikiQuiz questionnumber="1" question="…'
{{toplink
|linkpage =WikiQuiz
|linktext = WikiQuiz
|pagetype=Quiz
|Review= '''Richard Hammond''' BSc BVetMed DipECVA DVA PhD MRCVS
}}<br>
<WikiQuiz
questionnumber="1"
question="How does the anti-emetic maropitant work?"
choice4="Antagonist at neurokinin (NK1) receptor"
choice1="Antagonist at histamine receptor"
choice3="Antagonist at muscarinic receptor"
choice5="Agonist at dopamine 2 (D2) receptor"
choice2="Antagonist at 5-HT3 receptors"
correctchoice="4"
feedback4="'''Correct!''' Maropitant is a relatively new drug which has become licensed in the dog in the UK for treating vomiting and motion sickness. It works by antagonising the neurokinin (NK1) receptor. [[Emetics and Anti-Emetic Drugs#Anti-Emetics|anti-emetics.]]"
feedback1="'''Incorrect''' Histamine receptor antagonists e.g. diphenhydramine, are anti-emetics but maropitant works by antagonising the neurokinin (NK1) receptor. It is a relatively new drug which has become licensed in the dog in the UK for treating vomiting and motion sickness. [[Emetics and Anti-Emetic Drugs#Anti-Emetics|anti-emetics.]]"
feedback3="'''Incorrect''' Muscarinic receptor antagonists e.g. hyoscine, are anti-emetics but maropitant works by antagonising the neurokinin (NK1) receptor. It is a relatively new drug which has become licensed in the dog in the UK for treating vomiting and motion sickness. [[Emetics and Anti-Emetic Drugs#Anti-Emetics|anti-emetics.]]"
feedback5="'''Incorrect''' Dopamine 2 (D2) receptor agonists e.g. metoclopramide, are anti-emetics but maropitant works by antagonising the neurokinin (NK1) receptor. It is a relatively new drug which has become licensed in the dog in the UK for treating vomiting and motion sickness. [[Emetics and Anti-Emetic Drugs#Anti-Emetics|anti-emetics.]]"
feedback2="'''Incorrect'''5-HT3 receptor antagonists e.g. ondansetron, are anti-emetics but maropitant works by antagonising the neurokinin (NK1) receptor. It is a relatively new drug which has become licensed in the dog in the UK for treating vomiting and motion sickness. [[Emetics and Anti-Emetic Drugs#Anti-Emetics|anti-emetics.]]"
image= "">
</WikiQuiz>
<WikiQuiz
questionnumber="2"
question="How does the anti-emetic ondansetron work?"
choice5="Antagonist at 5-HT3 receptors"
choice1="Agonist at dopamine 2 (D2) receptor"
choice2="Antagonist at muscarinic receptor"
choice3="Antagonist at histamine receptor"
choice4="Antagonist at neurokinin (NK1) receptor"
correctchoice="5"
feedback5="'''Correct!''' Ondansetron is a 5-HT3 receptor antagonist, which works by directly inhibiting the chemoreceptor trigger zone and thus inhibiting the vomiting centre. [[Emetics and Anti-Emetic Drugs#Anti-Emetics|anti-emetics.]]"
feedback1="'''Incorrect''' Dopamine 2 (D2) receptor agonists e.g. metoclopramide, are anti-emetics but ondansetron is a 5-HT3 receptor antagonist. It works by directly inhibiting the chemoreceptor trigger zone and thus inhibiting the vomiting centre. [[Emetics and Anti-Emetic Drugs#Anti-Emetics|anti-emetics.]]"
feedback2="'''Incorrect''' Muscarinic receptor antagonists e.g. hyoscine, are anti-emetics but ondansetron is a 5-HT3 receptor antagonist. It works by directly inhibiting the chemoreceptor trigger zone and thus inhibiting the vomiting centre. [[Emetics and Anti-Emetic Drugs#Anti-Emetics|anti-emetics.]]"
feedback3="'''Incorrect''' Histamine receptor antagonists e.g. diphenhydramine, are anti-emetics but ondansetron is a 5-HT3 receptor antagonist. It works by directly inhibiting the chemoreceptor trigger zone and thus inhibiting the vomiting centre. [[Emetics and Anti-Emetic Drugs#Anti-Emetics|anti-emetics.]]"
feedback4="'''Incorrect''' Neurikinin (NK1) receptor antagonists e.g. maropitant, are anti-emetics but ondansetron is a 5-HT3 receptor antagonist. It works by directly inhibiting the chemoreceptor trigger zone and thus inhibiting the vomiting centre. [[Emetics and Anti-Emetic Drugs#Anti-Emetics|anti-emetics.]]"
image= "">
</WikiQuiz>
<WikiQuiz
questionnumber="3"
question="What is the pharmacological mechanism of action of omeprazole?"
choice1="Proton pump inhibitor"
choice3="Antacid"
choice2="Histamine (H2) Receptor Antagonist"
choice4="Binding agent"
choice5="Prostaglandin E Analogue"
correctchoice="1"
feedback1="'''Correct!''' Omeprazole is a proton pump inhibitor which works by binding irreversibly to the H+/K+/ATPase pump and so reducing the secretion of H+ from parietal cells. Omeprazole has a long duration of action as it binds irreversibly to the proton pump. [[Gastroprotective Drugs#Histamine .28H2.29 Receptor Antagonists|proton pump inhibitors.]]"
feedback3="'''Incorrect''' Antacids e.g. magnesium hydroxide,work by chemically neutralising the acidic environment of the stomach. Omeprazole is a proton pump inhibitor which works by binding irreversibly to the H+/K+/ATPase pump and so reducing the secretion of H+ from parietal cells. Omeprazole has a long duration of action as it binds irreversibly to the proton pump. [[Gastroprotective Drugs#Histamine .28H2.29 Receptor Antagonists|proton pump inhibitors.]]"
feedback2="'''Incorrect''' Histamine receptor antagonists e.g. ranitidine, work by inhibiting the action of histamine on parietal cells. This results in reduced production of H+ ions and pepsin secretion. Omeprazole is a proton pump inhibitor which works by binding irreversibly to the H+/K+/ATPase pump and so reducing the secretion of H+ from parietal cells. Omeprazole has a long duration of action as it binds irreversibly to the proton pump. [[Gastroprotective Drugs#Histamine .28H2.29 Receptor Antagonists|proton pump inhibitors.]]"
feedback4="'''Incorrect''' Binding agents e.g. sucralfate, work by forming a viscous paste in an acidic environment, the binds and protects the mucosal surface. They also stimulate mucus and bicarbonate secretion and the production of prostaglandins. Omeprazole is a proton pump inhibitor which works by binding irreversibly to the H+/K+/ATPase pump and so reducing the secretion of H+ from parietal cells. Omeprazole has a long duration of action as it binds irreversibly to the proton pump. [[Gastroprotective Drugs#Histamine .28H2.29 Receptor Antagonists|proton pump inhibitors.]]"
feedback5="'''Incorrect''' Prostaglandin E Analogues e.g. misoprostol, work by mimicking the endogenously produced prostaglandins that are gastroprotective. This will therefore inhibit H+ production and increase mucus and bicarbonate production. It will also maintain normal mucosal blood flow. Omeprazole is a proton pump inhibitor which works by binding irreversibly to the H+/K+/ATPase pump and so reducing the secretion of H+ from parietal cells. Omeprazole has a long duration of action as it binds irreversibly to the proton pump. [[Gastroprotective Drugs#Histamine .28H2.29 Receptor Antagonists|proton pump inhibitors.]]"
image= "">
</WikiQuiz>
<WikiQuiz
questionnumber="Gastrointestinal pharmacology quiz/3"
question="What is the pharmacological mechanism of action of ranitidine?"
choice5="Histamine (H2) receptor antagonist"
choice4="Antacid"
choice1="Proton pump inhibitor"
choice3="Binding agent"
choice2="Prostaglandin E Analogue"
correctchoice="5"
feedback5="'''Correct!''' Ranitidine is a histamine receptor antagonist which works by inhibiting the action of histamine on parietal cells. This results in reduced production of H+ ions and pepsin secretion. [[Gastroprotective Drugs#Histamine .28H2.29 Receptor Antagonists|histamine receptor antagonist.]]"
feedback4="'''Incorrect''' Antacids e.g. magnesium hydroxide,work by chemically neutralising the acidic environment of the stomach. Ranitidine is a histamine receptor antagonist which works by inhibiting the action of histamine on parietal cells. This results in reduced production of H+ ions and pepsin secretion. [[Gastroprotective Drugs#Histamine .28H2.29 Receptor Antagonists|histamine receptor antagonist.]]"
feedback1="'''Incorrect''' Proton pump inhibitors e.g. omeprazole, work by binding irreversibly to the H+/K+/ATPase pump and so reducing the secretion of H+ from parietal cells. Omeprazole has a long duration of action as it binds irreversibly to the proton pump. Ranitidine is a histamine receptor antagonist which works by inhibiting the action of histamine on parietal cells. This results in reduced production of H+ ions and pepsin secretion. [[Gastroprotective Drugs#Histamine .28H2.29 Receptor Antagonists|histamine receptor antagonist.]]"
feedback3="'''Incorrect''' Binding agents e.g. sucralfate, work by forming a viscous paste in an acidic environment, the binds and protects the mucosal surface. They also stimulate mucus and bicarbonate secretion and the production of prostaglandins. Ranitidine is a histamine receptor antagonist which works by inhibiting the action of histamine on parietal cells. This results in reduced production of H+ ions and pepsin secretion. [[Gastroprotective Drugs#Histamine .28H2.29 Receptor Antagonists|histamine receptor antagonist.]]"
feedback2="'''Incorrect''' Prostaglandin E Analogues e.g. misoprostol, work by mimicking the endogenously produced prostaglandins that are gastroprotective. This will therefore inhibit H+ production and increase mucus and bicarbonate production. It will also maintain normal mucosal blood flow. Ranitidine is a histamine receptor antagonist which works by inhibiting the action of histamine on parietal cells. This results in reduced production of H+ ions and pepsin secretion. [[Gastroprotective Drugs#Histamine .28H2.29 Receptor Antagonists|histamine receptor antagonist.]]"
image= "">
</WikiQuiz>
[[Category:Clinical_Quizzes]][[Category:Drug_Quizzes]]
|linkpage =WikiQuiz
|linktext = WikiQuiz
|pagetype=Quiz
|Review= '''Richard Hammond''' BSc BVetMed DipECVA DVA PhD MRCVS
}}<br>
<WikiQuiz
questionnumber="1"
question="How does the anti-emetic maropitant work?"
choice4="Antagonist at neurokinin (NK1) receptor"
choice1="Antagonist at histamine receptor"
choice3="Antagonist at muscarinic receptor"
choice5="Agonist at dopamine 2 (D2) receptor"
choice2="Antagonist at 5-HT3 receptors"
correctchoice="4"
feedback4="'''Correct!''' Maropitant is a relatively new drug which has become licensed in the dog in the UK for treating vomiting and motion sickness. It works by antagonising the neurokinin (NK1) receptor. [[Emetics and Anti-Emetic Drugs#Anti-Emetics|anti-emetics.]]"
feedback1="'''Incorrect''' Histamine receptor antagonists e.g. diphenhydramine, are anti-emetics but maropitant works by antagonising the neurokinin (NK1) receptor. It is a relatively new drug which has become licensed in the dog in the UK for treating vomiting and motion sickness. [[Emetics and Anti-Emetic Drugs#Anti-Emetics|anti-emetics.]]"
feedback3="'''Incorrect''' Muscarinic receptor antagonists e.g. hyoscine, are anti-emetics but maropitant works by antagonising the neurokinin (NK1) receptor. It is a relatively new drug which has become licensed in the dog in the UK for treating vomiting and motion sickness. [[Emetics and Anti-Emetic Drugs#Anti-Emetics|anti-emetics.]]"
feedback5="'''Incorrect''' Dopamine 2 (D2) receptor agonists e.g. metoclopramide, are anti-emetics but maropitant works by antagonising the neurokinin (NK1) receptor. It is a relatively new drug which has become licensed in the dog in the UK for treating vomiting and motion sickness. [[Emetics and Anti-Emetic Drugs#Anti-Emetics|anti-emetics.]]"
feedback2="'''Incorrect'''5-HT3 receptor antagonists e.g. ondansetron, are anti-emetics but maropitant works by antagonising the neurokinin (NK1) receptor. It is a relatively new drug which has become licensed in the dog in the UK for treating vomiting and motion sickness. [[Emetics and Anti-Emetic Drugs#Anti-Emetics|anti-emetics.]]"
image= "">
</WikiQuiz>
<WikiQuiz
questionnumber="2"
question="How does the anti-emetic ondansetron work?"
choice5="Antagonist at 5-HT3 receptors"
choice1="Agonist at dopamine 2 (D2) receptor"
choice2="Antagonist at muscarinic receptor"
choice3="Antagonist at histamine receptor"
choice4="Antagonist at neurokinin (NK1) receptor"
correctchoice="5"
feedback5="'''Correct!''' Ondansetron is a 5-HT3 receptor antagonist, which works by directly inhibiting the chemoreceptor trigger zone and thus inhibiting the vomiting centre. [[Emetics and Anti-Emetic Drugs#Anti-Emetics|anti-emetics.]]"
feedback1="'''Incorrect''' Dopamine 2 (D2) receptor agonists e.g. metoclopramide, are anti-emetics but ondansetron is a 5-HT3 receptor antagonist. It works by directly inhibiting the chemoreceptor trigger zone and thus inhibiting the vomiting centre. [[Emetics and Anti-Emetic Drugs#Anti-Emetics|anti-emetics.]]"
feedback2="'''Incorrect''' Muscarinic receptor antagonists e.g. hyoscine, are anti-emetics but ondansetron is a 5-HT3 receptor antagonist. It works by directly inhibiting the chemoreceptor trigger zone and thus inhibiting the vomiting centre. [[Emetics and Anti-Emetic Drugs#Anti-Emetics|anti-emetics.]]"
feedback3="'''Incorrect''' Histamine receptor antagonists e.g. diphenhydramine, are anti-emetics but ondansetron is a 5-HT3 receptor antagonist. It works by directly inhibiting the chemoreceptor trigger zone and thus inhibiting the vomiting centre. [[Emetics and Anti-Emetic Drugs#Anti-Emetics|anti-emetics.]]"
feedback4="'''Incorrect''' Neurikinin (NK1) receptor antagonists e.g. maropitant, are anti-emetics but ondansetron is a 5-HT3 receptor antagonist. It works by directly inhibiting the chemoreceptor trigger zone and thus inhibiting the vomiting centre. [[Emetics and Anti-Emetic Drugs#Anti-Emetics|anti-emetics.]]"
image= "">
</WikiQuiz>
<WikiQuiz
questionnumber="3"
question="What is the pharmacological mechanism of action of omeprazole?"
choice1="Proton pump inhibitor"
choice3="Antacid"
choice2="Histamine (H2) Receptor Antagonist"
choice4="Binding agent"
choice5="Prostaglandin E Analogue"
correctchoice="1"
feedback1="'''Correct!''' Omeprazole is a proton pump inhibitor which works by binding irreversibly to the H+/K+/ATPase pump and so reducing the secretion of H+ from parietal cells. Omeprazole has a long duration of action as it binds irreversibly to the proton pump. [[Gastroprotective Drugs#Histamine .28H2.29 Receptor Antagonists|proton pump inhibitors.]]"
feedback3="'''Incorrect''' Antacids e.g. magnesium hydroxide,work by chemically neutralising the acidic environment of the stomach. Omeprazole is a proton pump inhibitor which works by binding irreversibly to the H+/K+/ATPase pump and so reducing the secretion of H+ from parietal cells. Omeprazole has a long duration of action as it binds irreversibly to the proton pump. [[Gastroprotective Drugs#Histamine .28H2.29 Receptor Antagonists|proton pump inhibitors.]]"
feedback2="'''Incorrect''' Histamine receptor antagonists e.g. ranitidine, work by inhibiting the action of histamine on parietal cells. This results in reduced production of H+ ions and pepsin secretion. Omeprazole is a proton pump inhibitor which works by binding irreversibly to the H+/K+/ATPase pump and so reducing the secretion of H+ from parietal cells. Omeprazole has a long duration of action as it binds irreversibly to the proton pump. [[Gastroprotective Drugs#Histamine .28H2.29 Receptor Antagonists|proton pump inhibitors.]]"
feedback4="'''Incorrect''' Binding agents e.g. sucralfate, work by forming a viscous paste in an acidic environment, the binds and protects the mucosal surface. They also stimulate mucus and bicarbonate secretion and the production of prostaglandins. Omeprazole is a proton pump inhibitor which works by binding irreversibly to the H+/K+/ATPase pump and so reducing the secretion of H+ from parietal cells. Omeprazole has a long duration of action as it binds irreversibly to the proton pump. [[Gastroprotective Drugs#Histamine .28H2.29 Receptor Antagonists|proton pump inhibitors.]]"
feedback5="'''Incorrect''' Prostaglandin E Analogues e.g. misoprostol, work by mimicking the endogenously produced prostaglandins that are gastroprotective. This will therefore inhibit H+ production and increase mucus and bicarbonate production. It will also maintain normal mucosal blood flow. Omeprazole is a proton pump inhibitor which works by binding irreversibly to the H+/K+/ATPase pump and so reducing the secretion of H+ from parietal cells. Omeprazole has a long duration of action as it binds irreversibly to the proton pump. [[Gastroprotective Drugs#Histamine .28H2.29 Receptor Antagonists|proton pump inhibitors.]]"
image= "">
</WikiQuiz>
<WikiQuiz
questionnumber="Gastrointestinal pharmacology quiz/3"
question="What is the pharmacological mechanism of action of ranitidine?"
choice5="Histamine (H2) receptor antagonist"
choice4="Antacid"
choice1="Proton pump inhibitor"
choice3="Binding agent"
choice2="Prostaglandin E Analogue"
correctchoice="5"
feedback5="'''Correct!''' Ranitidine is a histamine receptor antagonist which works by inhibiting the action of histamine on parietal cells. This results in reduced production of H+ ions and pepsin secretion. [[Gastroprotective Drugs#Histamine .28H2.29 Receptor Antagonists|histamine receptor antagonist.]]"
feedback4="'''Incorrect''' Antacids e.g. magnesium hydroxide,work by chemically neutralising the acidic environment of the stomach. Ranitidine is a histamine receptor antagonist which works by inhibiting the action of histamine on parietal cells. This results in reduced production of H+ ions and pepsin secretion. [[Gastroprotective Drugs#Histamine .28H2.29 Receptor Antagonists|histamine receptor antagonist.]]"
feedback1="'''Incorrect''' Proton pump inhibitors e.g. omeprazole, work by binding irreversibly to the H+/K+/ATPase pump and so reducing the secretion of H+ from parietal cells. Omeprazole has a long duration of action as it binds irreversibly to the proton pump. Ranitidine is a histamine receptor antagonist which works by inhibiting the action of histamine on parietal cells. This results in reduced production of H+ ions and pepsin secretion. [[Gastroprotective Drugs#Histamine .28H2.29 Receptor Antagonists|histamine receptor antagonist.]]"
feedback3="'''Incorrect''' Binding agents e.g. sucralfate, work by forming a viscous paste in an acidic environment, the binds and protects the mucosal surface. They also stimulate mucus and bicarbonate secretion and the production of prostaglandins. Ranitidine is a histamine receptor antagonist which works by inhibiting the action of histamine on parietal cells. This results in reduced production of H+ ions and pepsin secretion. [[Gastroprotective Drugs#Histamine .28H2.29 Receptor Antagonists|histamine receptor antagonist.]]"
feedback2="'''Incorrect''' Prostaglandin E Analogues e.g. misoprostol, work by mimicking the endogenously produced prostaglandins that are gastroprotective. This will therefore inhibit H+ production and increase mucus and bicarbonate production. It will also maintain normal mucosal blood flow. Ranitidine is a histamine receptor antagonist which works by inhibiting the action of histamine on parietal cells. This results in reduced production of H+ ions and pepsin secretion. [[Gastroprotective Drugs#Histamine .28H2.29 Receptor Antagonists|histamine receptor antagonist.]]"
image= "">
</WikiQuiz>
[[Category:Clinical_Quizzes]][[Category:Drug_Quizzes]]