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''[[Actinobacillus pleuropneumoniae]]''
 
''[[Actinobacillus pleuropneumoniae]]''
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''[[Actinobacillus equuli]]''
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===''Actinobacillus equuli''===
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*Commensal of the equine intestinal and reproductive tract
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*Pathogenesis and clinical signs:
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**Foals infected ''in utero'' or or after birth via the umbilicus
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**Infection at birth causes severe enteritis and septicaemia within 24 hours, known as sleepy foal disease
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**Foals become pyrexic and recumbent
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**Death usually occurs within 1-2 days
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**In foals that survive neonatal infection the condition progresses to cause joint infections and purulent nephritis, enteritis or pneumonia
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**''A. equuli'' in [[Joints Inflammatory - Pathology#In Horses|arthritis of horses]]
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**Abortion, septicaemia and [[Peritoneal Cavity Inflammatory - Pathology#In horses|peritonitis in horses]]
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*Diagnosis:
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**Specimens cultured on blood agar and MacConkey agar and incubated aerobically for 1-3 days
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**Sticky colonies with variable haemolysis on blood agar
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**Lactose-fermenting colonies on MacConkey agar
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*Treatment and control:
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**Antimicrobials ineffective unless early in course of disease
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**Blood trasfusion and administration of colostrum
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**Good hygiene
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**Consider prophylactic antibiotics for new-born foals
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**Bacteria susceptible to streptomycin, tetracyclines and ampicillin
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*In other animals:
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**Septicaemia in piglets
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**Arthritis and enteritis in pigs
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**Enteritis in calves
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**RTX group cytotoxin present
       
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