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| *Live in nasopharyngeal and oral mucosa | | *Live in nasopharyngeal and oral mucosa |
| *Cause pyogranulomatous lesions | | *Cause pyogranulomatous lesions |
− | **''Actinomyces bovis'' | + | |
− | ***Found naturally in oral cavity of cattle
| + | |
− | ***Prefers anaerobic conditions but not strict anaerobe
| + | **''[[Actinomyces bovis]]'' |
− | ***Entry of organism into tissues following trauma to the mucosa from rough feed or tooth eruption
| + | |
− | ***Causes [[Chronic Inflammation - Pathology#Granulomatous Inflammation|granulomatous inflammation]] of soft tissues and bone, causing [[Teeth - Pathology#Mandibular Osteomyelitis|lumpy jaw]]
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− | ***Usually invades mandible to cause [[Bones Inflammatory - Pathology#Osteomyelitis|osteomyelitis]] and may extend to surrounding [[Muscles Inflammatory - Pathology#Actinomycosis bovis|muscles]]
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− | ***The lesions begins as a painless swelling of the affected bone
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− | ***Swelling becomes more painful and enlarges over a number of weeks, gaining fistulous tracts which discharge pus
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− | ***Organisms found in yellow sulphur granules
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− | ***Club colony formation
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− | ***Colonies adhere to agar media and are non-haemolytic
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− | ***Surgical treatment possible when lesions are small
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− | ***Prolonged parenteral penicillin treatment may be beneficial early in the disease
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| **''Actinomyces viscosus'' | | **''Actinomyces viscosus'' |
| ***Commensal of oral cavity of dogs and humans | | ***Commensal of oral cavity of dogs and humans |