Changes

on the circumstances, the species of bacteria will vary. For example Gram-negative

on the circumstances, the species of bacteria will vary. For example Gram-negative

species from faecal contamination will often infect a wound on

species from faecal contamination will often infect a wound on

the foot or distal limb. [[Staphylococcus spp.|Staphylococcal]] and [[Streptococci|Streptococcal]] infections are

the foot or distal limb. [[:Category:Staphylococcus species|Staphylococcal]] and [[Streptococci|Streptococcal]] infections are

common contaminants of skin wounds because they may be normal skin

common contaminants of skin wounds because they may be normal skin

commensals.

commensals.

a profound effect on healing by destruction of the collagen matrix, and so

a profound effect on healing by destruction of the collagen matrix, and so

the inflammatory response cannot effectively close the wound. Infection

the inflammatory response cannot effectively close the wound. Infection

with ''Staphylococcus aureus'' can cause pyogranuloma within the wound site.

with ''[[Staphylococcus aureus]]'' can cause pyogranuloma within the wound site.

Clinically this resembles both granulation tissue and [[Sarcoid - Donkey|sarcoid]].

Clinically this resembles both granulation tissue and [[Sarcoid - Donkey|sarcoid]].