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*Phenothiazine which was used as an anthelmintic
 
*Phenothiazine which was used as an anthelmintic
 
*Tetracycline - if one injects bitches with tetracycline when pregnant, puppies are born with brown [[Oral Cavity - Teeth & Gingiva - Anatomy & Physiology|teeth]], which fluoresce under UV light.  
 
*Tetracycline - if one injects bitches with tetracycline when pregnant, puppies are born with brown [[Oral Cavity - Teeth & Gingiva - Anatomy & Physiology|teeth]], which fluoresce under UV light.  
*Haemosiderin may also produce pinky / brown colour to [[Oral Cavity - Teeth & Gingiva - Anatomy & Physiology|teeth]] usually due to damage and haemorrhage into [[Oral Cavity - Teeth & Gingiva - Anatomy & Physiology|tooth]].[[Category:Teeth_-_Developmental_Pathology]]
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*Haemosiderin may also produce pinky / brown colour to [[Oral Cavity - Teeth & Gingiva - Anatomy & Physiology|teeth]] usually due to damage and haemorrhage into [[Oral Cavity - Teeth & Gingiva - Anatomy & Physiology|tooth]].
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*'''Primary'''
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**Ingestion of photodynamic substance from plants (''Hypericum perforatum'' and ''Fagopyrum sagittatum'' - buckwheat) or fungal contaminants
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**Induced by drug administration - phenothiazines, tetracyclines, thiazides, sulphonamides
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*'''Abnormal porphyrin metabolism'''
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**Bovine congenital porphyria
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**Bovine erythropoeitic protoporphyria
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*'''Hepatogenous'''
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**Impaired excretion of phylloerythrin (chlorophyl metabolism product) due to hepatic disease
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**[[Liver Biliary Tract - Pathology#Obstruction|Biliary obstruction]]
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**Inherited defects
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**Hepatic injury due to toxic plants or fungal contaminants, chemicals or some infectious agents
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*Grossly:
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**In areas lacking hair or pigment
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**Erythema, oedema -> blisters, exudation, necrosis, sloughing or keratitis
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*Microscopically:
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**Subepidermal vesicles
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**Ulceration
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**Secondary infection
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[[Category:Teeth_-_Developmental_Pathology]]
 
[[Category:Liver_-_General_Pathology]]
 
[[Category:Liver_-_General_Pathology]]
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