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Category:Liver - Storage Diseases (view source)

Revision as of 13:31, 7 June 2010

929 bytes removed , 13:31, 7 June 2010

Replaced content with '==Lysosomal Storage Disease== ==Amyloidosis== Category:Liver_-_Pathology'

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==[[Lysosomal Storage Disease]]==

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==~~Amyloidosis==~~

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==[[Amyloidosis]]==

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*amyloid infiltration occurs in all species

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*an inert substance deposited under the endothelium and basement membranes of a variety of tissues

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**renal glomeruli

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**[[~~Pancreas - Anatomy & Physiology#Endocrine|Islets of Langerhans~~]] ~~in the [[Pancreas - Anatomy & Physiology|pancreas]]~~

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**[[Liver - Anatomy & Physiology|liver]] (between the sinusoidal reticulum and the hepatic cords)

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~~====Causes====~~

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~~May be a primary condition or appear secondary to some chronic tissue destructive process~~

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*an infectious process elsewhere in the body

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*a result of sustained antigenic stimulation, eg repeated injections with an antigenic substance or production of excessive antibody by leukocytes

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~~====Gross====~~

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*pale (greyish waxy appearance)

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*enlarged

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*rounded edges

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*firm

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*very prone to rupture

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~~====Microscopically==~~==

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*deposition of amyloid in the space of Disse

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*shows 'apple-green' fluorescence under polarised light after staining with Congo Red

[[Category:Liver_-_Pathology]]

Bara

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