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***Serovar ''bratislava'' causes abortion and infertility in dogs, which may be the maintenance host
***Serovar ''bratislava'' causes abortion and infertility in dogs, which may be the maintenance host
***Infections uncommon in cats
***Infections uncommon in cats
*''Leptospirosis icterohaemorrhagica'' - a septicaemic disease which affects the [[Liver - Anatomy & Physiology|liver]]
*puppies
*Leptospirosis is an important spirochaetal group of diseases causing disease in animals and humans (zoonotic)
*Transmission
**via urine of affected animals
**organisms can remain viable for weeks in damp conditions
*method of action
**cause anaemia via intravascular haemolysis
=====Clinical=====
*fever
*dehydration
*haemorrhaging from the mucous membranes of the body
=====Diagnosis=====
*dark field microscopy on fresh urine is best
=====Gross=====
*widespread hameorrhages
*icterus
*pale foci in the [[Liver - Anatomy & Physiology|liver]] (not always a constant finding)
*subcapsular and cortical renal haemorrhages
=====Microscopically=====
*foci of necrosis
*dissociation of hepatocytes form each other (similar to post mortem change)
*substantial haemosiderin in the Kuppfer cells (from the haemolysis)
*need to use a silver stain or immunofluorescence to demonstrate the organisms in tissues
[[Category:Leptospiraceae]][[Category:Cat]][[Category:Dog]]
[[Category:Leptospiraceae]][[Category:Cat]][[Category:Dog]]
[[Category:Hepatitis,_Bacterial]]