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==In Pigs==
 
==In Pigs==
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===Inclusion body rhinitis===
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[[Porcine Cytomegalovirus]]
[[Image:Inclusion body rhinitis.jpg|right|thumb|100px|<small><center>Inclusion body rhinitis (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
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*[[Herpesviridae|'''Herpesviridae, porcine cytomegalovirus''']]
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*Disease of suckling piglets 1-5 wks of age
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*Clinical signs: those associated with acute/subacute [[Nasal Cavity Inflammatory - Pathology#Infectious causes of rhinitis|rhinitis]] (ie: serous nasal discharge, progressing to catarrhal or purulent discharge with time and secondary bacterial infections; sneezing; pyrexia), fever in young piglets (3-8wks old)
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*May progress to [[Paranasal Sinuses Inflammatory - Pathology#Sinusitis|sinusitis]], otitis media or [[Lungs Inflammatory - Pathology#Infectious causes of pneumonia|pneumonia]]
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*Morbitity high, mortality low
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*Gross pathology - catarrhal discharge becoming purulent (secondary infection)
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*Histology:
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**Large basophilic [[Degenerations and Infiltrations - Pathology#Cellular Inclusions|intranuclear inclusion bodies]] in the surface and subepithelium of nasal and sinus glandular epithelium with lymphocytic infiltration of the mucosa
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**Bursting of nucleus with cell necrosis and sloughing of necrotic epithelium
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*Can develop viraemic stage, with inclusions and focal necrotising lesions in other organs eg: renal tubular epithelium
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**Usually younger piglets, can die during this phase
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*Usually resolves if uncomplicated but rhinitis may persist if secondary infection is present
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*May persist in pulmonary macrophages
       
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