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===Clinical===
 
===Clinical===
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The infection primarily affects the intestine, and causes thickening of the mucosal wall. This causes impaired function, affecting its absorptive ability.  This may cause, severe emaciation, and chronic profuse diarrhoea.
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* Clinical signs develop in older cows after calving i.e. 3 to 4 years of age.   
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Clinical signs may also develop in older cows during times of stress; around calving for example.
* '''BUT'''  animals are infected as calves less than 6 months old
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** The disease develops very slowly.
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In advances cases the infected animal gradually fades away and dies over the course of months.
* Clinical signs include:
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** Ongoing, chronic profuse diarrhoea.
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*** Paint like consistency.
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** Hindquarters and tail-caked with faeces
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** Faeces also splattered on walls.
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** Animal gradually fades away and dies over the course of months.
      
===Pathogenesis===
 
===Pathogenesis===
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