Line 1: Line 1: −
{{dog}}
+
{{OpenPagesTop}}
{{cat}}
+
Also known as: '''''Calcifying epithelial odontogenic tumour
 +
 
 +
==Introduction==
 +
The lesions are slow growing and locally invasive.The most prominent feature of this type of tumour is that it produces amyloid which tends to calcify.
 +
 
 
==Typical Signalment==
 
==Typical Signalment==
*This is a common odontogenic tumour in cats.
+
This is a rare tumour seen more often in cats and than in dogs.
*More rarely found in dogs.
     −
==Description==
  −
The lesions appear as masses that are friable and ulcerated. Many amyloid-producing odontogenic tumours are [[Neoplasia - Pathology#Nomenclature|melanotic]] which makes them difficult to distinguish from the more aggressive malignant melanoma. They can erode but not infiltrate adjacent bone.
  −
   
==Diagnosis==
 
==Diagnosis==
   
===Clinical Signs===
 
===Clinical Signs===
*halitosis
+
Include halitosis, oral bleeding, dental disruption or loss, facial or mandibular deformity, excessive salivation, growth protruding from the mouth and rarely dysphagia.
*oral bleeding
  −
*dental disruption or loss
  −
*facial or mandibular deformity
  −
*excessive salivation
  −
*growth protruding from the mouth
  −
*dysphagia occurs rarely
   
   
 
   
 
===Diagnostic Imaging===
 
===Diagnostic Imaging===
Skull radiography may show a soft tissue opacity  with mineralization within the mass. Periosteal reaction of the adjacent bone may be visualised. If a malignant neoplasm is a dignostic possibility, thoracic radiography should be carried out to evaluate for lung metastases.
+
Skull radiography may show a soft tissue opacity  with mineralization within the mass. Periosteal reaction of the adjacent bone may be visualised. If a malignant neoplasm is a diagnostic possibility, thoracic radiography should be carried out to evaluate for lung metastases.
 +
 
 
===Biopsy===
 
===Biopsy===
 
+
Biopsy is required for a definitive diagnosis.
Required for a definitive diagnosis
+
Incisional biopsy is the best option, when undertaking cytological or grab procedures it is difficult to obtain a representative sample.
*Incisional Biopsy - best
  −
*Cytological or grab procedures - difficult to obtain a representative sample
      
Histologically, the tumour appears to be well demarcated from the surrounding tissue but is not encapsulated.
 
Histologically, the tumour appears to be well demarcated from the surrounding tissue but is not encapsulated.
    
==Treatment==
 
==Treatment==
*Surgical excision with narrow margins is normally sufficient.
+
Surgical excision with narrow margins is normally sufficient.  
*Radiation therapy should be considered in cases of incomplete surgical excision.
+
Radiation therapy should be considered in cases of incomplete surgical excision.
    
==Prognosis==
 
==Prognosis==
*Good following complete surgical excision.
+
Good following complete surgical excision however recurrance following incomplete surgical excision is possible.
*Recurrance following incomplete surgical excision is possible.
+
 
 +
{{Learning
 +
|literature search = [http://www.cabdirect.org/search.html?q=%28%28%28%22Amyloid+producing+Odontogenic+Tumor%22%29+OR+%28%22Calcifying+epithelial+odontogenic+tumor%22+%29%29%29+OR+%28%28%28%22Amyloid+producing+Odontogenic+Tumour%22%29+OR+%28%22Calcifying+epithelial+odontogenic+tumour%22+%29%29%29 Amyloid-producing Odontogenic Tumour publications]
 +
|Vetstream = [https://www.vetstream.com/felis/Content/Disease/dis02424.asp Amyloidosis]
 +
}}
 +
 
 
==References==
 
==References==
   −
*Tutt, C., Deeprose, J. and Crossley, D. (2007) '''BSAVA Manual of Canine and Feline Dentistry (3rd Edition)''' ''BSAVA''
+
Tutt, C., Deeprose, J. and Crossley, D. (2007) '''BSAVA Manual of Canine and Feline Dentistry (3rd Edition)''' ''BSAVA''
 +
 
 +
Merck & Co (2008) '''The Merck Veterinary Manual (Eighth Edition)''' ''Merial''
 +
 
 +
 
 +
{{review}}
 +
 
 +
{{OpenPages}}
 +
 
 +
[[Category:Oral Diseases - Cat]][[Category:Oral_Cavity_-_Proliferative_Pathology]][[Category:Teeth_-_Proliferative_Pathology]]
   −
*Merck & Co (2008) '''The Merck Veterinary Manual'''
  −
[[Category:Cat]][[Category:Oral_Cavity_-_Proliferative_Pathology]][[Category:Teeth_-_Proliferative_Pathology]]
  −
[[Category:To_Do_-_Clinical]]
   
[[Category:Neoplasia]]
 
[[Category:Neoplasia]]
 +
 +
[[Category:Oral Diseases - Dog]]
 +
[[Category:Expert Review - Small Animal]]
 +
[[Category:Oral Proliferations]]
 +
[[Category:LisaM reviewing]]
147

edits