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==Treatment==
==Treatment==
The underlying cause of the renal failure should be treated. To alleviate the clinial signs of uraemia, it is particularly important to restrict phosphate by feeding a '''low phosphate diet''' and using '''phosphate-binding drugs''' such as aluminium hydroxide or chitosan. Deficient electroylytes should be supplemented but calcium should only be administered after hyperphosphataemia has been corrected to prevent further mineralisation of soft tissues.
The underlying cause of the renal failure should be treated. To alleviate the clinial signs of uraemia, it is particularly important to restrict phosphate by feeding a '''low phosphate diet''' and using '''phosphate-binding drugs''' such as aluminium hydroxide or chitosan. Deficient electroylytes should be supplemented but calcium should only be administered after hyperphosphataemia has been corrected to prevent further mineralisation of soft tissues.
Various [[Gastroprotective Drugs|gastro-protectant drugs]] can be prescribed to manage the gastro-intestinal signs of uraemia, including sucralfate and the acid secretory inhibitors ranitidine, cimetidine and omeprazole. Appetite stimulants such as mirtazapine can also be administered to anorexic animals to encourage voluntary food intake.
A major advance in the management of uraemia has been the introduction of '''recombinant erythropoietin''' which can be administered to anaemic animals as a series of subcutaneous injections. Some animals may become resistant to its effects over time due to the development of an immune response to the recombinant protein.
A major advance in the management of uraemia has been the introduction of '''recombinant erythropoietin''' which can be administered to anaemic animals as a series of subcutaneous injections. Some animals may become resistant to its effects over time due to the development of an immune response to the recombinant protein.