Line 46: |
Line 46: |
| | | |
| | | |
− | Mammary involvement is now rarely seen, the uterine form is also uncommon but may reult in abortion. | + | Mammary involvement is now rarely seen; the uterine form is also uncommon but may result in abortion. |
| | | |
| ===Laboratory Tests=== | | ===Laboratory Tests=== |
| | | |
− | An ELISA test has been developed but is not widely used. The gamma interferon test can also be used for diagnosis of the condtion. | + | An ELISA test has been developed but is not widely used. The gamma interferon test can also be used for diagnosis of the condition. |
| | | |
| ===Pathology=== | | ===Pathology=== |
| | | |
| Findings at post mortem depend on the route of entry of the organism, whether it became generalised or not and the stage of the disease. | | Findings at post mortem depend on the route of entry of the organism, whether it became generalised or not and the stage of the disease. |
− | One or more lymph nodes will display the chacteristic granulomatous tubercules. In the respiratory form the mediastinal and bronchial lymph nodes are affected, with lesions in the lungs. | + | One or more lymph nodes will display the characteristic granulomatous tubercles. In the respiratory form the mediastinal and bronchial lymph nodes are affected, with lesions in the lungs. |
| | | |
| If the mycobacteria disseminated from the primary complex then lymph nodes in other regions will also be affected and there will be multiple small foci of infection on other organs. | | If the mycobacteria disseminated from the primary complex then lymph nodes in other regions will also be affected and there will be multiple small foci of infection on other organs. |
Line 63: |
Line 63: |
| Treatment is not usually an option due to the chronic nature of the disease, zoonotic potential and test and slaughter policy. | | Treatment is not usually an option due to the chronic nature of the disease, zoonotic potential and test and slaughter policy. |
| | | |
− | Control in many countries is centered on tuberculin testing with slaughter of reactors and movement restrictions to the premises. | + | Control in many countries is centred on tuberculin testing with slaughter of reactors and movement restrictions to the premises. |
− | Research work continues into the use of vacination, or a cull strategy for the associated wildlife populations. | + | Research work continues into the use of vaccination, or a cull strategy for the associated wildlife populations. |
| | | |
| ==Prognosis== | | ==Prognosis== |
Line 70: |
Line 70: |
| Poor. | | Poor. |
| | | |
− | | + | |
| ==References== | | ==References== |
| *Andrews, A.H, Blowey, R.W, Boyd, H and Eddy, R.G. (2004) '''Bovine Medicine''' (Second edition), ''Blackwell Publishing'' | | *Andrews, A.H, Blowey, R.W, Boyd, H and Eddy, R.G. (2004) '''Bovine Medicine''' (Second edition), ''Blackwell Publishing'' |