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CAV1 was first isolated by Carbasso in 1954 <sup>1</sup>from a case of acute hepatitis in the dog. This virus found to be identical to the virus isolated in 1947 by Rubarth<sup>2</sup> from a dog showing acute liver lesions, and so CAV1 was originally known as Infectious Canine Hepatitis (ICH) virus. Subsequently, CAV1 infection was shown to be common in young dogs worldwide, with 82% of British dogs displaying neutralising antibody titres by nine months of age<sup>3</sup>. It has also since been demonstrated that CAV1 has a role in diseases other than infectious canine hepatitis, and CAV1 infection has been the subject of many studies.  
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Canine Adenovirus 1 (CAV-1) was first isolated by Carbasso in 1954<sup>1</sup> from a case of acute hepatitis in the dog. This virus found to be identical to the virus isolated in 1947 by Rubarth<sup>2</sup> from a dog showing acute liver lesions, and so CAV-1 was originally known as Infectious Canine Hepatitis (ICH) virus. Subsequently, CAV1 infection was shown to be common in young dogs worldwide, with 82% of British dogs displaying neutralising antibody titres by nine months of age<sup>3</sup>. It has also since been demonstrated that CAV1 has a role in diseases other than [[Infectious Canine Hepatitis]], such as [[Canine Infectious Tracheobronchitis]].
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Causes [[Canine Infectious Tracheobronchitis]]
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CH is caused by a nonenveloped DNA virus, canine  adenovirus 1 (CAV-1),  which is antigenically related only to CAV-2 (one  of the causes of  infectious canine tracheobronchitis,                  Infectious  Tracheobronchitis of Dogs). CAV-1 is  resistant to lipid solvents and  survives outside the host for weeks or  months, but a 1-3% solution of  sodium hypochlorite (household bleach) is  an effective disinfectant.
   
==Classification==
 
==Classification==
  
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