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| ====[[Equine Severe Combined Immune Deficiency]] ==== | | ====[[Equine Severe Combined Immune Deficiency]] ==== |
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− | ====Canine X-Linked Severe Combined Immune Deficiency (Canine SCID)==== | + | ====[[Canine X-Linked Severe Combined Immune Deficiency]] ==== |
− | *Affects Basset Hounds and Corgis
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− | *X-linked recessive defect in the gene coding for the IL-2 receptor
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− | **IL-2 receptor is a receptor for the cytokine IL-2 which causes [[Lymphocytes#T cells|T cells]] to proliferate
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− | *Causes lymphoid hypoplasia, stunted growth and increases the animal's susceptibility to infection
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− | *Animal usually dies from pneumonia or sepsis as the level of maternal [[Immunoglobulins|antibody]] decreases
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− | [[Category:Primary Adaptive Immunity Deficiencies]]
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− | [[Category:To Do - Blood]]
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| ====Selective [[IgA]] deficiency of German Shepherd Dogs==== | | ====Selective [[IgA]] deficiency of German Shepherd Dogs==== |
| *Poorly understood | | *Poorly understood |
| *Linked to other disease syndromes such as deep pyoderma, inflammatory bowel disease, anal furunculosis and disseminated aspergillosis | | *Linked to other disease syndromes such as deep pyoderma, inflammatory bowel disease, anal furunculosis and disseminated aspergillosis |
| *[[Immunoglobulin A|[[IgA]]]] deficiency so more susceptible to mucosal disease | | *[[Immunoglobulin A|[[IgA]]]] deficiency so more susceptible to mucosal disease |
− | [[Category:Primary Adaptive Immunity Deficiencies]] | + | [[Category:Primary Adaptive Immunity Deficiencies]][[Category:Dog]] |
| [[Category:To Do - Blood]] | | [[Category:To Do - Blood]] |
| ====Immunodeficiency of Weimaraners, Irish Wolfhounds and Miniature Dachshunds==== | | ====Immunodeficiency of Weimaraners, Irish Wolfhounds and Miniature Dachshunds==== |
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| **E.g. Pneumocytosis in Miniature Dachshunds due to low [[Immunoglobulin G|IgG]] | | **E.g. Pneumocytosis in Miniature Dachshunds due to low [[Immunoglobulin G|IgG]] |
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− | [[Category:Primary Adaptive Immunity Deficiencies]] | + | [[Category:Primary Adaptive Immunity Deficiencies]][[Category:Dog]] |
| [[Category:To Do - Blood]] | | [[Category:To Do - Blood]] |
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