Changes

<p>So named as they were initially found in the [[Bursa of Fabricius - Anatomy & Physiology|Bursa of Fabricius]]. They produce antibodies (Ig’s) and are associated with humoral immunity. They represent 20-30% of circulating lymphocytes.

<p>So named as they were initially found in the [[Bursa of Fabricius - Anatomy & Physiology|Bursa of Fabricius]]. They produce antibodies (Ig’s) and are associated with humoral immunity. They represent 20-30% of circulating lymphocytes.

B cells have B cell receptors (BCR), or antigen binding sites. This is [[IgM]] when the B cell is immature, changing to [[IgD]] when the cell is mature. B cells also express MHC II, CD9, CD,19, CD20 and CD24.</p>

B cells have B cell receptors (BCR), or antigen binding sites. This is [[IgM]] when the B cell is immature, changing to [[IgD]] when the cell is mature. B cells also express MHC II, CD9, CD,19, CD20 and CD24.</p>

<p>Under antigenic stimulation they differentiate into [[B cell differentiation - WikiBlood#Plasma cells|plasma cells]] and [[B cell differentiation - WikiBlood#Memory cells|memory cells]].</p>

<p>Under antigenic stimulation they differentiate into [[B cell differentiation#Plasma cells|plasma cells]] and [[B cell differentiation#Memory cells|memory cells]].</p>

B-cells also act as Antigen-Presenting Cells (APCs) by presenting digested fragments to T-cells on [[MHC - WikiBlood#MHC II|MHC II]].

B-cells also act as Antigen-Presenting Cells (APCs) by presenting digested fragments to T-cells on [[MHC - WikiBlood#MHC II|MHC II]].

For more on B cell differentiation, see [[B cell differentiation - WikiBlood|here]].

For more on B cell differentiation, see [[B cell differentiation|here]].

[[Category:Lymphocytes|C]]

[[Category:Lymphocytes|C]]