Changes

|<gallery>Image:Aspergillus in vivo.jpg|<center><p>'''Aspergillus in vivo'''</p>^{Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath}</center></gallery>

|<gallery>Image:Aspergillus in vivo.jpg|<center><p>'''Aspergillus in vivo'''</p>^{Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath}</center></gallery>

|}

|}

==Diagnosis==

==Diagnosis==

In dogs, radiology is often peformed in the diagnostic work up of an animal with suspected Aspergillosis. Open-mouth ventro-dorsal views often reveal generalised radiolucency and lysis of the turbinate bones. Rhinoscopy may be used to directly visualise the lesions, revealing characteristic white-green fungal plaques.

In dogs, radiology is often peformed in the diagnostic work up of an animal with suspected Aspergillosis. Open-mouth ventro-dorsal views often reveal generalised radiolucency and lysis of the turbinate bones. Rhinoscopy may be used to directly visualise the lesions, revealing characteristic white-green fungal plaques. Fungal culture can be used to demonstrate the organism but should not be used as the sole means of diagnosis due to the ubitquitous nature of Aspergillus in the environment. Aspergillus grows on Sabauraud's Dextrose and Blood agar. White colonies form intitially which turn green, then dark green, flat and velvety

*Grows on Sabauraud's Dextrose and Blood agar

**White colonies intitially which turn green, then dark green, flat and velvety

*Microscopically:

*Microscopically:

**Is a common contaminant so repeated tests should be done for a definitive diagnosis

**Is a common contaminant so repeated tests should be done for a definitive diagnosis

*Pathology:

*Pathology:

**Sometimes appears on [[Nasal Cavity Hyperplastic and Neoplastic - Pathology#Progressive ethmoidal haematoma|lesions of ethmoidal haematoma]]

**Sometimes appears on [[Nasal Cavity Hyperplastic and Neoplastic - Pathology#Progressive ethmoidal haematoma|lesions of ethmoidal haematoma]]

==Treatment==

==Treatment==

In dogs, the treatment of choice is topical application of Clotrimazole. It is admnistered via indwelling catheters placed through a trephine hole in the frontal sinus.

In dogs, the treatment of choice is topical application of the anti-fungal agent Clotrimazole. It is admnistered via indwelling catheters placed through a trephine hole in the frontal sinus.

 

 

 

|<gallery>Image:Aspergillus sporing heads.jpg|<center><p>'''Aspergillus sporing heads'''</p>^{Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath}</center>

|<gallery>Image:Aspergillus sporing heads.jpg|<center><p>'''Aspergillus sporing heads'''</p>^{Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath}</center>

Image:Mycelium aspergillus quink.jpg|<center><p>'''Aspergillus mycelium stained with blue/black Quink'''</p>^{Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath}</center>

Image:Mycelium aspergillus quink.jpg|<center><p>'''Aspergillus mycelium stained with blue/black Quink'''</p>^{Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath}</center>