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Laboratory mice strain information (view source)

Revision as of 13:00, 25 August 2010

217 bytes added , 13:00, 25 August 2010

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==C57BL/6 (B6) mice:==

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~~Background srain~~, ~~longelivity~~. Their melanism is manifested by their coat colour. melanin pigment in heart valves, splenic capsule and meninges.

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Gold standard background strain for GEM's, genome of this strain has been fully sequenced. B6 mice were initially bred for their longevity. Their melanism is manifested by their coat colour. melanin pigment in heart valves, splenic capsule and meninges.

'''Spontaneous diseases:'''

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Hydrocephalus, hippocampal neurodegeneration, microphtalmia, anophtalmia, age ~~realted~~ cochlear degeneration (hearing loss), malocclusion and pulmonary proteinosis.

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Hydrocephalus, hippocampal neurodegeneration, microphtalmia, anophtalmia, age-related cochlear degeneration (hearing loss), malocclusion and pulmonary proteinosis.

'''Common neoplasms:'''

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Lymphoma (especially B-cell), haemangiosarcoma, and pituitary adenoma (especially prolactin-secreting cells)

==BALB/c mice:==

Kerstin

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