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Atopic Dermatitis (view source)

Revision as of 18:42, 26 August 2010

430 bytes removed , 18:42, 26 August 2010

→‎Antihistamines

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however, resulted in a relapse in most dogs.

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~~====~~Antihistamines~~====~~

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Antihistamines have some efficacy in the face of atopic dermatitis, and may have synergistic activity with essential fatty acids and glucocorticoids<sup>4</sup>.

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~~A large review of clinical trials (16) concluded~~

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~~that there is no more than fair evidence of~~

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~~medium~~ efficacy ~~for~~ the ~~first generation antihistamines~~

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~~clemastine and a combination~~

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of ~~chlorpheniramine and hydroxyzine~~, and

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~~the second generation (non-sedating) drug~~

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~~oxatomide. There~~ may ~~however be some~~ synergistic

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activity with ~~EFAs~~ and glucocorticoids.

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~~Adverse effects of first generation drugs are~~

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~~uncommon and are usually linked to drowsiness.~~

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~~Adverse effects to second generation drugs~~

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~~are more common and include gastrointestinal~~

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~~tract upsets and cardiac arrhythmias~~.

==Prognosis==

Lizzies

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