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| | **Greater omentum- connceting the greater curvature of the stomach to the [[Duodenum - Anatomy & Physiology|duodenum]] and dorsal body wall | | **Greater omentum- connceting the greater curvature of the stomach to the [[Duodenum - Anatomy & Physiology|duodenum]] and dorsal body wall |
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| − | ==Histology== | + | ==[[Stomach - Histology|Histology]]== |
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| − | [[Image:Glandular Stomach Histology Dog.jpg|thumb|right|150px|Glandular Stomach Histology Dog- Copyright RVC 2008]] | |
| − | *Columnar epithelium
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| − | *Folded mucosa forming longitudinal rugae
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| − | *Invaginations called gastric pits which are continuous with gastric glands
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| − | *The 4 layers of the stomach wall are:
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| − | **Serosa/adventitia
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| − | **Tunica muscularis
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| − | **Submucosa
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| − | **Mucosa
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| − | *Chief (zygomatic) cells secreting pepsinogen
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| − | **Secreted in response to vagus and gastrin
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| − | **Basophilic
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| − | **More abundant in base of glands
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| − | **Pepsinogen unfolds and cleaves itself (autocatalyses) in response to hydrochloric acid
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| − | **Only active in acidic envrionments
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| − | [[Image:Fundic region of glandular stomach.jpg|thumb|right|150px|Fundic Region of Glandular Stomach (Parietal and Chief cells)- Copyright RVC 2008]]
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| − | *Goblet cells secreting mucous
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| − | **Protects against autodigestion
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| − | *Parietal (oxyntic) cells secreting hydrochloric acid in gastric pits
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| − | **Aids digestion
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| − | **Activates gastric enzymes, e.g. pepsinogen to pepsin
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| − | **Kills microorganisms and enzymes that enter with food
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| − | **Secreted in response to vagus or pepsin
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| − | **Large, pyramid shaped
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| − | **More abundant in upper region of glands
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| − | *Gastrin from pyloric G cells
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| − | *Somatostatin from pyloric D cells
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| − | *Histamine from Enterochromaffin-like cells (ECL cells)
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| − | [[Image:Lamina muscularis 3 regions.jpg|thumb|right|150px|Lamina Muscualris 3 Regions - Copyright RVC 2008]]
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| − | *3 layers of lamina muscularis: the outer longitudinal, middle circular and inner oblique.
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| − | *Glands are short, coiled, branched tubular. Need to be replaced due to wear and tear. Only in mucosal layer.
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| − | | |
| − | *Cardia is a narrow muscle strip
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| − | *Pyloric sphincter is thickened tunica muscularis from the middle circular smooth muscle layer
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| − | *In fundic region, tunica muscularis is thinner, glands are straight and gastric pits are shallow. Abundance of parietal and cheif cells in gland.
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| − | *In pyloric region, tunica muscularis is thicker, glands are coiled and gastric pits are deep.
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| − | *Lymphatic vessels are present in the submucosa
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| | ==Vasculature== | | ==Vasculature== |