Changes

===Dogs and Horse===

===Dogs and Horse===

[[Image:thrombosis dog nose.jpg|right|thumb|200px|<small><center>'''Nasal thrombosis (dog)'''. Courtesy of T. Scase</center></small>]]

[[Image:thrombosis dog nose.jpg|right|thumb|200px|<small><center>'''Nasal thrombosis (dog)'''. Courtesy of T. Scase</center></small>]]

* Cardiac thrombosis is generally of degenerative/ non-infectious cause.

Cardiac thrombosis is generally of degenerative/ non-infectious cause; endocarditis may occur, though uncommonly. There are important effects of cardiac thrombosis:

** Endocarditis may occur, though uncommonly.

# Distortion of valve cusps leads to mechanical effects which cause ineffective closure (incompetence), and distortion and enlargement of the valves by the thrombus mass causes narrowing of the valve outflow (stenosis). These effects lead to a progressive inefficiency of cardiac pumping and give rise to [[Venous Congestion and Hyperaemia - Pathology#Generalised (Systemic) Venous Congestion|general venous congestion]], [[Oedema - Pathology|oedema]] and circulatory failure.

* There are important effects of cardiac thrombosis.

*# Distortion of valve cusps leads to mechanical effects.

*#* Ineffective closeure gives leakage (incompetence).

*#* Distortion and enlargement of the valves by the thrombus mas fuves narrowing of the valve outflow (stenosis).

*#* These effects lead to progressive inefficiency of cardiac pumping.

*#** Causes [[Venous Congestion and Hyperaemia - Pathology#Generalised (Systemic) Venous Congestion|general venous congestion]], [[Oedema - Pathology|oedema]] and circulatory failure.

*# Emboli are disseminated from the thrombus mass.

*# Emboli are disseminated from the thrombus mass.

*#* If the lesion is on the left side of the heart, emboli are disseminated systemically.

*#* If the lesion is on the left side of the heart, emboli are disseminated systemically.