Dendritic cells stimulate a primary T cell response; they migrate through tissues, track to T cell dependent areas of the [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] and cluster with the T cells. Dendritic cells have unique capabilities to take up antigen by pathways involving phagocytosis, macropinocytosis and clathrin-coated pits. The cell-surface antigen phenotype distinguishes the dendritic cell from [[Monocytes]]/macrophages and [[B cells]]. Their main function is priming of T helper cells.
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Dendritic cells stimulate a primary T cell response; they migrate through tissues, track to T cell dependent areas of the [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] and cluster with the T cells. Dendritic cells have unique capabilities to take up antigen by pathways involving phagocytosis, macropinocytosis and clathrin-coated pits. The cell-surface antigen phenotype distinguishes the dendritic cell from [[Monocytes]]/macrophages and [[B cells]]. Their main function is priming T helper cells. They produce cell signaling cytocline molecules known as [[Cytokines#Chemokines|chemokines]].