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T cell differentiation (view source)
Revision as of 07:55, 27 September 2010
, 07:55, 27 September 2010→T-Cell Activation
==T-Cell Activation==
==T-Cell Activation==
T cells function only after recent activation by an antigen.
T cells function only after recent activation by an antigen.
* CD4 binds [[Major Histocompatability Complexes#MHC II|MHC class II]] - [[T_cells#Helper_CD4.2B|CD4+ T-cells]] recognise antigen only in association with [[Major Histocompatability Complexes#MHC II|MHC class II]].
* CD4 binds MHC class II - [[T_cells#Helper_CD4.2B|CD4+ T-cells]] recognise antigen only in association with [[Major Histocompatability Complexes#MHC II|MHC class II]].
* CD8 binds [[Major Histocompatability Complexes#MHC I|MHC class I]] - [[Lymphocytes#Cytotoxic CD8+|CD8+ T-cells]] recognise antigen only in association with [[Major Histocompatability Complexes#MHC I|MHC class I]].
* CD8 binds MHC class I - [[T_cells#Cytotoxic_CD8.2B|CD8+ T-cells]] recognise antigen only in association with [[Major Histocompatability Complexes#MHC I|MHC class I]].
* Activation of [[Lymphocytes#T cells|T cells]] requires two distinct signals.
* Activation of [[Lymphocytes#T cells|T cells]] requires two distinct signals.
** '''Signal 1'''
** '''Signal 1'''