Changes

Also known as: '''''Bacillary Typhilitis

Also known as: '''''Bacillary Typhilitis

Tyzzer's disease is caused by the obligatory intracellular ''Clostridium (formerly Bacillus) piliformis'', a gram-variable organism diagnosed on post-mortem examination by histopathology utilising Giemsa or Warthin-Starry staining techniques (Walden 1990). The organism may be seen on impression smears of the ileum lining (see Okerman 1994). The organism does not grow on broth or agar. Predisposing causes in rabbits are not known (Carman 1994) but weanlings are most frequently affected.  

Tyzzer's disease is caused by the obligatory intracellular [[Clostridium piliforme|''Clostridium (formerly Bacillus) piliformis'']], a gram-variable organism diagnosed on post-mortem examination by histopathology utilising Giemsa or Warthin-Starry staining techniques (Walden 1990). The organism may be seen on impression smears of the ileum lining (see Okerman 1994). The organism does not grow on broth or agar. Predisposing causes in rabbits are not known (Carman 1994) but weanlings are most frequently affected.  

Symptoms include acute depression, watery diarrhoea and a high mortality rate) or chronic weight loss.  Post-mortem findings include dehydration, oedema of the intestinal wall, necrosis of the colonic and caecal mucosa, and occasionally many necrotic foci in the liver.  

Symptoms include acute depression, watery diarrhoea and a high mortality rate) or chronic weight loss.  Post-mortem findings include dehydration, oedema of the intestinal wall, necrosis of the colonic and caecal mucosa, and occasionally many necrotic foci in the liver.