Changes

[[Image:2000px-Coagulation full svg.png|right|thumb|320px|<p>'''Coagulation Cascade''' Source: Wikimedia Commons. Author: Joe D (2007)</p>]]

[[Image:2000px-Coagulation full svg.png|right|thumb|325px|<p>'''Coagulation Cascade''' Source: Wikimedia Commons. Author: Joe D (2007)</p>]]

==Introduction==

==Introduction==

Factor deficiencies are often the result of congenital deficiency in one or more of the coagulation factors. Deficiencies lead to ineffective blood clotting and development of a disease syndrome characterized by excessive bleeding - deficiencies are often detected following trauma or surgery. Occasionally bleeding may be spontaneous (e.g. into alimentary or urinary tracts). Deficiencies are often seen as familial inherited problems. Haemophilia (factor VIII deficiency) is probably the best understood condition.

Factor deficiencies are often the result of congenital deficiency in one or more of the coagulation factors. Deficiencies lead to ineffective blood clotting and development of a disease syndrome characterized by excessive bleeding - deficiencies are often detected following trauma or surgery. Occasionally bleeding may be spontaneous (e.g. into alimentary or urinary tracts). Deficiencies are often seen as familial inherited problems. Haemophilia (factor VIII deficiency) is probably the best understood condition.