Changes

==Factors affecting Responses to Toxins==

==Factors affecting Responses to Toxins==

===Species===

===Species===

Some toxins are specific to certain species - chocolate poisoning in dogs for example could in theory affect cats in a similar way but their dietary habits mean they are far less likely to consume large quantities of chocolate of their own volition. Cats lack some glucuronyl transferases that are important for glucuronidation, so drugs such as aspirin, paracetamol, morphine and hexachlorophene have a prolonged half life because these chemicals are metabolised and excreted as glucuronide conjugates. In terms of toxicity, this mechanism increases the risk of accumulation and therefore increases the likelyhood of toxic effects occuring.

Some toxins are specific to certain species - chocolate poisoning in dogs for example could in theory affect cats in a similar way but their dietary habits mean they are far less likely to consume large quantities of chocolate of their own volition. Cats lack some glucuronyl transferases that are important for glucuronidation, so drugs such as aspirin, paracetamol, morphine and hexachlorophene have a prolonged half life because these chemicals are metabolised and excreted as glucuronide conjugates. In terms of toxicity, this mechanism increases the risk of accumulation and therefore increases the likelihood of toxic effects occuring.

===Age===

===Age===