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'''Cholangitis''' is the inflammation of the biliary tract.  '''Cholangiohepatitis''' is the inflammation of the biliary tract and the surrounding hepatic parenchyma.  It is typically categorised into [[Cholangitis, Neutrophilic|Neutrophilic Cholangitis]] and [[Cholangitis, Lymphocytic|Lymphocytic Cholangitis]].
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==Introduction==
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Cholangitis describes an inflammation of the biliary tract.  Cholangiohepatitis describes the inflammation of the biliary tract and the surrounding hepatic parenchyma.  It is typically categorised into [[Cholangitis, Neutrophilic|Neutrophilic Cholangitis]] and [[Cholangitis, Lymphocytic|Lymphocytic Cholangitis]].
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==Signalment==
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Cholangitis is common in cats, where a periportal hepatocellular necrosis is seen together with
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the presence of neutrophils in the portal area. Cats can be acutely or chronicaly affected, and 
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male, pure bred cats are most overly prepresented.
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The condition is also seen in calves as a secondary condition to bacterial infection, such as Salmonella.
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*Inflammation of the bile ducts
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===Causes===
 
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*ascending infections from the intestine where stasis of bile flow has developed
**common in cats
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*associated with organisms excreted via the bile such as salmonellosis infection in calves
**calves eg ''Salmonella sp.''
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===Causes===
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==Laboratory Findings==
*ascending infections from the intestine
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Raised ALT and serum bilirubin levels.
**requires stasis of bile flow to develop
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*associated with organisms excreted via the bile
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**salmonellosis infection in calves
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==Cats==
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***cholangitis
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***periportal hepatocellular necrosis
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***neutrophils in the portal areas
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***acute or chronic.
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***Usually male, pure bred
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*** Cats more ill than lymphocytic portal hepatitis.
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***Higher ALT and serum bilirubin levels.
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===Chronic lymphocytic cholangitis===
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==Histology==
*mature cats
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Lymphocytic infiltration of the portal areas is seen, with mild fibrosis and biliary hyperplasia.
====Microscopically====
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*lymphocytic infiltration of the portal areas
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*mild fibrosis
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*biliary hyperplasia
      
==Test yourself with the Liver Pathology Flashcards==
 
==Test yourself with the Liver Pathology Flashcards==
   
[[Liver_Flashcards_-_Pathology|Liver Pathology Flashcards]]
 
[[Liver_Flashcards_-_Pathology|Liver Pathology Flashcards]]
  
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