Ergot Poisoning

• Caused by ingestion of grains or grass contaminated by fungus Claviceps purpurae
• Affects especially cattle
• Toxic alkaloids damage capillary endothelium, peripheral arterial and venous constriction -> thrombosis and possible tissue ischaemia
• Clinical signs develop about a week after consumption
• Grossly:
  • Red and swollen extremities
  • Dry gangrene may develop on pinnae and tail