Injection Site Reaction

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Revision as of 16:05, 21 February 2011 by Bara (talk | contribs) (Created page with "*May be caused by subcutaneous injections *Granulomatous nodules form with central necrotic and foreign material *Macrophages and multinucleated giant cells around the centre *Su...")

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  • May be caused by subcutaneous injections
  • Granulomatous nodules form with central necrotic and foreign material
  • Macrophages and multinucleated giant cells around the centre
  • Surrounded by granulation tissue, perivascular lymphocytes that may form lymphoid follicles, eosinophils
  • Cats may develop fibrosarcomas secondary to vaccination
  • Dogs, especially poodles, may develop lymphoplasmacytic panniculitis and perivasculitis, vasculitis and follicular atrophy secondary to killed rabies vaccine