Panosteitis

Panosteitis (Image sourced from Bristol Biomed Image Archive with permission)

• Typically young large or giant breeds
• 75% of cases in German shepherd dogs, 5-12 months old
• Clinical signs:
  • Shifting lameness
  • Often eosinophilia in peripheral blood
• Usually self-limiting in one to several months
• Grossly:
  • Foreleg long bone diaphyses affected (multiple bones in 50% of cases)
  • Increased bone formation in the medullary cavity and often in the periosteum
• Contast with hypertrophic osteodystrophy