Immunoglobulins Flashcards

From WikiVet English
Jump to navigation Jump to search
WikiBloodWikiBlood Banner.png
IMMUNOGLOBULINS
WIKIBLOOD FLASHCARDS


Immunoglobulins Structure and Function

Question Answer Article
What are immunoglobulins also known as?
  • Antibodies
Link to Answer Article
How many domains does the heavy chain have?
  • 1 variable domain
  • 3 or 4 constant domains
Link to Answer Article
How many domains does the light chain have?
  • 1 variable domain
  • 1 constant domain
Link to Answer Article
What are hypervariable domains?
  • Folded pockets of the variable domain into which antibody can bind
  • Different antibodies have different amino acid sequences within the three varibale domains
Link to Answer Article
What does Fab stand for and from which chain is it generated?
  • Fragment associated with antigen binding
  • Light chain
Link to Answer Article
What does Fc stand for and from which chain is it generated?
  • Constant fragment
  • Heavy chain
Link to Answer Article
What does the Fc fragment do?
  • Mediates phagocytosis
  • Triggers inflammation
  • Targets Ig to certain tissues
Link to Answer Article
What are the four major effects of antibodies?
  • Blockage and agglutination
  • Promotion of phagocytosis
  • Degranulation of mast cells/eosinophils
  • Complement Fixation
Link to Answer Article