Parvoviridae
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Introduction
Parvoviruses are cleverly named for their extreme size (parve=small). They are species-specific and serious gastroenteric infections.
Morphology
- Small, non-enveloped, icosahedral DNA virus with featureless virions
Virulence and Pathogenesis
- Resistant to pH (even gastric acidity), heat, and desiccation
- Infect rapidly dividing cells
- Target bone marrow, intestinal epithelium, and growing fetus (via viremia)
- Causes Parvovirus Enteritis
Epidemiology
- Can persist for years in the environment