Drugs Acting on the Intestines
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Drugs Increasing Smooth Muscle Contractility
These drugs are used for conditions that are associated with hypomotility, such as megacolon, oesophageal reflux, atony and ileus.
Drugs Acting on 5-HT4 Receptors
- An examples is metoclopramide that is an agonist at serotonin and dopamine receptors, this results in an increased release of acetylcholine and so increases gut motility.
Muscarinic Receptor Agonists
- Examples are carbachol and bethanecol. They should be used with slight caution as their resultant contractions can be painful.