Pasteurella multocida
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- Large grey colonies on blood agar
- Not haemolytic
- Do not grow on MacConkey
- Five capsular serotypes, A,B,D,E and F
- Primary and secondary pathogen
- Responsible for secondary infections following primary viral and mycoplasmal infections, especially in the lungs, for example during Enzootic pneumonia of calves and pigs
- Can cause vascular fragility, leading to haemorrhagic disease
- Involved in subcutaneous abscesses due to cat bites
- Typa A
- Commensal in upper respiratory tract of animals in UK
- Primary pathogen in avian cholera - a septicaemia in chickens and turkeys
- Secondary pathogen commomly repsonsible for dog and cat bite wound infections in humans and animals
- Feline pyothorax and cellulitis
- Some strains involved in Atrophic rhinitis of pigs, and produce osteolytic toxin
- Involved in 'Snuffles' in rabbits, a mucopurulent rhinosinitis
- Can cause pneumonia and mastitis in sheep
- Associated with pneumonic pasteurellosis in cattle, as well as enzootic pneumonia in calves
- Type B
- Causes Haemorrhagic Septicaemia of cattle in Southern Europe and Asia
- Type D
- Primary and secondary pathogen
- Causes atrophic rhinitis along with Bordetella bronchiseptica in pigs
- Pneumonia in pigs
- Pasteurella multocida adhere to epithelium damaged by Bordetella bronchiseptica
- Produces an osteolytic toxin (Pmt), which stimulates osteoclasts, inducing bone resorption of the nasal turbinates
- Type E
- Causes African Bovine Haemorrhagic Septicaemia