Sendai Virus
Revision as of 12:37, 12 June 2010 by A.allison (talk | contribs) (Text replace - 'Lymphocytes - WikiBlood' to 'Lymphocytes')
Murine Parainfluenza - 1 (Sendai Virus)
- Endemic in many mouse colonies
- Most mice show no symptoms due to maternal antibodies
- But minor respiratory lesions may invalidate carcinogenic or toxicological studies
- Immunological studies also confused due to virus activating NK cells via high circulating IF 3-4 days post-infection
- Control achieved by:
- Purchasing specific pathogen free (SPF) mice
- Kill whole colony in an outbreak -> disinfection -> formalin fumigation