Category:Lymph Nodes

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Category:Lymph Node Responses in Disease


Role of the Lymph Node in Inflammation

Back to Inflammation - Pathology

Diseases Involving Reactive Node Diseases

Diseases Parasitising the Lymphocytes

  • organism grows in the lymphocytes and ruptures them
  • if large infecting dose
- may be rapidly fatal since animal may no tb e able to mount an immunological attack
  • if smaller infecting dose
- loss of mature lymphocytes causes a dramatic stimulation of the remaining lymphocyte precursors
- node hyperplasia follows
- competition between lymphocytolysis by the organism and lymphocyte production by the nodes
- clinically
- may be swelling of the node at one stage and reduction in size at another

canine distemper

  • virus

swine fever

  • virus

bovine east coast fever

  • protozoan

Leishmaniasis in the dog


Other Lymphadenopathy

Lymph node pigmentation

  • Lungs
- anthracosis
- carbon derived from soot finds its way to the local nodes in macrophages
  • Skin
- dermatopathic lymphadenopathy or melanic reticulosis
- in pigmented animals, especially black dogs
- chronic inflammatory skin conditions lead to melanin deposition in hyperplastic nodules
- also occurs in nodes draining skin melanomas where the pigment may be the result of skin ulceration or secondary tumour deposit
- these two should not be confused since the prognosis is very different following surgery

Emphysema

  • interstitial emphysema
- common in cases of dyspnoea
- more commonly affects bovine lung
- due to well developed pulmonary lobulation and hence much loose interstitial lung tissue
  • collection of gas bubbles in bronchial and mediastinal lymph nodes
- gas travels to these nodes after gaining entry to the many lymphatic vessels present in the interstitial tissue

Neoplasia

  • Primary tumours
    • Lymphosarcoma (lymphoma)
- of lymphoid cells with lymph node enlargement
- smooth, pale hemogenous but may have areas of necrosis
- may cause pseudo-hyperparathyroidism
  • Secondary tumours
- nodes often involved in the spread of tumours by extension or metastasis
- usually carcinomas

Haemal Lymph Nodes

Pages in category "Lymph Nodes"

The following 5 pages are in this category, out of 5 total.