Category:Primary Innate Immunity Deficiencies
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Deficiencies of Innate Immunity
Canine Cyclic Haematopoiesis
Canine Leukocyte Adhesion Deficiency (CLAD)
- Occurs in Irish Setters
- Missence mutation of -Cys-36-Ser- in CD18 molecule
- CD18 is required for neutrophil migration and phagocytosis
- Recurrent bacterial infection
- Neutrophilia (neutrophils remain in the blood and are unable to fight infection in the tissue)
Bovine Leukocyte Adhesion Deficiency (BLAD)
- Occurs in Holstein cattle
- Missence mutation of -Asp-128-Gly in CD18 molecule
- Recurrent infection, e.g. pneumonia
Pages in category "Primary Innate Immunity Deficiencies"
The following 3 pages are in this category, out of 3 total.