Cytokines Flashcards

Cytokines

Question	Answer	Article
Cytokines produced by myeloid cells are commonly known as what?	Monokines	Link to Answer Article
Cytokines responsible for directing cell migration are commonly known as what?	Chemokines	Link to Answer Article
What type of cytokines are produced by cells in response to viral infection?	Interferons	Link to Answer Article
IL-12, produced primarily by macrophages, stimulates what subtype of helper T cells?	Th1	Link to Answer Article
What cytokine stimulates local inflammation and endothelial activation?	TNF-α	Link to Answer Article
What cytokine activates macrophages and increases MHC expression?	IFN-γ	Link to Answer Article
What cytokine, produced primarily by Th2 cells, activates B cells and the IgE switch?	IL-4	Link to Answer Article
What two groups can the chemokines be classed as, based on the cysteine residue position?	C-C C-X-C	Link to Answer Article
What are the main actions of the chemokines?	Lymphoid trafficking Wound healing Th1/Th2 development Angiogenesis Lymphoid organ development Inflammation Cell recruitment	Link to Answer Article
What is the main cause of bacterial septic shock?	Bacterial cell wall endotoxins	Link to Answer Article
What is the main cause of bacterial toxic shock?	Bacterial superantigens	Link to Answer Article
The symptoms of bacterial septic and toxic shock are caused mainly by the release of which cytokines?	TNF IL-1	Link to Answer Article