In Vitro Maturation - Anatomy & Physiology

Of interest for breeding guide dogs, which are monoetrous animals that do not produce many mature oocytes. This is desirable to avoid bitches having to take leave due to pregnancy.
Experimental with low success rates.
Routine in mice.
Recovery of secondary or primary (ultimately primordial) follicles.
Oocytes are arrested in the germinal vesicle stage (prophase of the first meiotic division).
Follicles matured in vitro for subsequent IVF.
Donor should be pre-pubertal, thus a full pool of primordial follicles is available.

Navigation menu