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Guaifenesin, a centrally acting skeletal muscle relaxant with only mild sedative and analgesic effects, can be administered intravenously to donkeys in combination with xylazine and ketamine for extended periods of general anaesthesia (Matthews and Taylor, 2000). Careful monitoring of the depth of anaesthesia is essential, particularly because donkeys are more sensitive
 
Guaifenesin, a centrally acting skeletal muscle relaxant with only mild sedative and analgesic effects, can be administered intravenously to donkeys in combination with xylazine and ketamine for extended periods of general anaesthesia (Matthews and Taylor, 2000). Careful monitoring of the depth of anaesthesia is essential, particularly because donkeys are more sensitive
 
(40% less required to produce recumbency) to guaifenesin than horses (Matthews et al, 1997; Matthews and Taylor, 2000). '''Overdosage''' is associated with abnormal respiration nystagmus, hypotension, and contradictory muscle rigidity.
 
(40% less required to produce recumbency) to guaifenesin than horses (Matthews et al, 1997; Matthews and Taylor, 2000). '''Overdosage''' is associated with abnormal respiration nystagmus, hypotension, and contradictory muscle rigidity.
      
==Suggested combination regimens for sedative/tranquillisers, opioids and anaesthetic agents in donkeys==
 
==Suggested combination regimens for sedative/tranquillisers, opioids and anaesthetic agents in donkeys==
Author, Donkey, Bureaucrats, Administrators
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