Antibiotic Responsive Diarrhoea
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Signalment
- Common in young German Shepherd Dogs
Description
Antibiotic responsive diarrhoea (ARD) used to be termed as small intestinal bacterial overgrowth (SIBO). It is a sign of an underlying disease rather than a diagnosis. The aetiology and pathogenesis of this disease is unknown.
The effect of ARD are:
- interferance with fluid and nutritional absorption due to dysfunction of the enzymes located at the microvillous.
- disturbance in mucosal permeability.
- deconjugation of bile acids.
- hydroxylation of fatty acids.
ARD can be claasified as idiopathic or secondary. In cases of idiopathic ARD, the only consistent finding is response and remission on antimicrobial therapy. In contrast, there is usually an underlying intestinal disease in cases of secondary ARD.
Diagnosis
Clinical Signs
Laboratory Tests
Haematology
Biochemistry
Other Tests
Diagnostic Imaging
Histopathology
Treatment
Prognosis
References
- Ettinger, S.J. and Feldman, E. C. (2000) Textbook of Veterinary Internal Medicine Diseases of the Dog and Cat Volume 2 (Fifth Edition) W.B. Saunders Company.
- Hall, E.J, Simpson, J.W. and Williams, D.A. (2005) BSAVA Manual of Canine and Feline Gastroenterology (2nd Edition) BSAVA
- Nelson, R.W. and Couto, C.G. (2009) Small Animal Internal Medicine (Fourth Edition) Mosby Elsevier.